Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750471 | 0.79 | KIF11 (0.47) | KIF11ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6854133 | 0.79 | KIF11 (0.47) | KIF11ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL10276699 | 0.78 | KIF11 (0.46) | KIF11ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL12225852 | 0.75 | KIF11 (0.49) | KIF11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4363002 | 0.75 | KIF11 (0.49) | KIF11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14356107 | 0.74 | KIF11 (0.49) | KIF11ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL30610089 | 0.74 | KIF11 (0.49) | KIF11ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9040716 | 0.74 | KIF11 (0.50) | KIF11MAPTALDH1A1MEN1KMT2A | |
| Succinic Acid SCHEMBL6854675 | 0.74 | KIF11 (0.54) | KIF11NPC1RAB9AKCNH2 | |
| SCHEMBL28885052 | 0.73 | KIF11 (0.49) | KIF11ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165569-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | Agilent Technologies, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056740-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | PROLINX, INC. (US) | 2000-09-28 | — | — | WO | disclosed |