Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615942 | 0.80 | MAPT (0.34) | MAPTHSD17B10 | |
| SCHEMBL7615947 | 0.80 | MAPT (0.34) | MAPTHSD17B10 | |
| SCHEMBL7615945 | 0.80 | MAPT (0.34) | MAPTHSD17B10 | |
| SCHEMBL10033567 | 0.79 | TSHR (0.42) | TSHRUSP2MCL1MAPTCTSS | |
| SCHEMBL14521485 | 0.76 | KMT2A (0.41) | TSHRUSP2MCL1KMT2AMAPT | |
| SCHEMBL27787604 | 0.75 | USP2 (0.45) | TSHRUSP2KMT2AMAPTALDH1A1 | |
| SCHEMBL1772263 | 0.73 | — | — | |
| SCHEMBL2563763 | 0.73 | ALDH1A1 (0.38) | TSHRUSP2MCL1KMT2AMAPT | |
| SCHEMBL11126550 | 0.73 | USP2 (0.56) | TSHRUSP2KMT2AMAPTALDH1A1 | |
| SCHEMBL8212374 | 0.72 | GNAI3 (0.46) | TSHRUSP2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046524-C | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1999-11-17 | — | — | CN | disclosed |
| CN-1105365-A | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1995-07-19 | — | — | CN | disclosed |