SCHEMBL7616189

SCHEMBL7616189

O=C(C=Cc1cccc(C(=O)O)c1C(=O)O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
RAB9A P51151 4/20 0.53
BCHE P06276 3/20 0.53
NPC1 O15118 3/20 0.53
LMNA P02545 2/20 0.53
MAOB P27338 4/20 0.51
CYP1B1 Q16678 2/20 0.51
PLIN1 O60240 1/20 0.51
TNFRSF1A P19438 1/20 0.51
ACHE P22303 1/20 0.51
RECQL P46063 1/20 0.51
PLIN5 Q00G26 1/20 0.51
ABHD5 Q8WTS1 1/20 0.51
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
P4HB P07237 1/20 0.49
TYR P14679 1/20 0.49
NFKB1 P19838 3/20 0.47
NFKB2 Q00653 3/20 0.47
RELA Q04206 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925836 1.00 MAPT (0.53) MAPTRAB9ABCHENPC1LMNA
SCHEMBL9319237 0.86 MAPT (0.58) MAPTRAB9ABCHENPC1LMNA
SCHEMBL6311040 0.86 MAPT (0.58) MAPTRAB9ABCHENPC1LMNA
SCHEMBL10341680 0.84 MAPT (0.53) MAPTRAB9ABCHENPC1LMNA
SCHEMBL10341679 0.84 MAPT (0.53) MAPTRAB9ABCHENPC1LMNA
SCHEMBL1649383 0.84 MAPT (0.56) MAPTRAB9ABCHENPC1LMNA
SCHEMBL27621963 0.83 RAB9A (0.55) MAPTRAB9ABCHENPC1LMNA
SCHEMBL4619018 0.81 ALDH1A1 (0.48) MAPTLMNAKMT2AALDH1A1HPGD
SCHEMBL9006476 0.80 MAPT (0.69) MAPTRAB9ABCHENPC1LMNA
SCHEMBL8640255 0.80 PTPN1 (0.54) MAPTBCHENFKB1ALDH1A1GUSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3349863-B1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2022-01-19 EP claimed
CN-109092361-B Rare earth metal organic complex based on chalcone dicarboxylic acid ligand and preparation method and application thereof 嘉兴学院 2021-08-13 CN claimed
CN-108440278-B Dicarboxy chalcone compound and its application in preparing anti-inflammatory medicine 中国计量大学 2021-01-12 CN claimed
CN-108997383-B Metal organic framework compound and preparation method and application thereof 嘉兴学院 2020-12-01 CN claimed
CN-108997383-A Metal organic framework compound and its preparation method and application 嘉兴学院 2018-12-14 CN claimed
EP-2866783-B1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2018-01-10 EP claimed
EP-2866899-B1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2017-12-27 EP claimed
CN-109092361-B Rare earth metal organic complex based on chalcone dicarboxylic acid ligand and preparation method and application thereof 嘉兴学院 2021-08-13 CN disclosed
CN-109092361-B Rare earth metal organic complex based on chalcone dicarboxylic acid ligand and preparation method and application thereof 嘉兴学院 2021-08-13 CN disclosed
CN-109092361-B Rare earth metal organic complex based on chalcone dicarboxylic acid ligand and preparation method and application thereof 嘉兴学院 2021-08-13 CN disclosed
CN-108440278-B Dicarboxy chalcone compound and its application in preparing anti-inflammatory medicine 中国计量大学 2021-01-12 CN disclosed
CN-108997383-B Metal organic framework compound and preparation method and application thereof 嘉兴学院 2020-12-01 CN disclosed
CN-108997383-B Metal organic framework compound and preparation method and application thereof 嘉兴学院 2020-12-01 CN disclosed
US-5250652-A High loading water-dispersible UVA and/or UVB light-absorbing copolymer LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-10-05 US disclosed
US-5243021-A Polylactam, polyester, polyether copolymers containing stilbene groups LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-09-07 US disclosed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP disclosed
EP-0248932-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-09 EP disclosed
EP-0248932-A1 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-12-16 EP disclosed
EP-0009223-B1 PHOTOSENSITIVE COMPOSITION MITSUBISHI KASEI CORPORATION (JP) 1982-11-10 EP disclosed
US-4258124-A Photosensitive composition MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1981-03-24 US disclosed