Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983809 | 0.93 | CES2 (0.59) | CES2CES1PARP10KMT2AMAPT | |
| SCHEMBL9699295 | 0.89 | MAPT (0.49) | CES2CES1PARP10KMT2AMAPT | |
| SCHEMBL28635017 | 0.87 | PARP10 (0.47) | CES2CES1PARP10KMT2AMAPT | |
| SCHEMBL12199140 | 0.85 | PARP10 (0.62) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL725405 | 0.84 | PARP10 (0.77) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL9339348 | 0.84 | KMT2A (0.53) | CES2CES1PARP10KMT2AMAPT | |
| SCHEMBL4905240 | 0.84 | KMT2A (0.62) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL8210785 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL1546405 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL10608864 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444099-B | Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof | 浙江大学城市学院 | 2022-06-21 | — | — | CN | disclosed |
| EP-1150673-A4 | MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS | NEWLAXANT L L C (US) | 2002-04-24 | — | — | EP | disclosed |
| CN-1338934-A | Mono-acyloxy aralkyl neuronuscular relaxants | NEWLAXANT L L C (US) | 2002-03-06 | — | — | CN | disclosed |
| EP-1150673-A1 | MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS | Newlaxant, L.L.C. (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000044377-A1 | MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS | NEWLAXANT, L.L.C. (US) | 2000-08-03 | — | — | WO | disclosed |
| US-5288871-A | Modify balance between rates of bone resorption and formation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| US-4335052-A | OXIDATION OF CORRESPONDING BENZYL HALIDE WITH TERITARY AMINE OXIDEIN PRESENCE OF WATER | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |