Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4216005 | 0.87 | KMT2A (0.54) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL2755026 | 0.85 | KMT2A (0.68) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL7616356 | 0.84 | CES2 (0.59) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL18566943 | 0.81 | KMT2A (0.56) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL8983809 | 0.81 | CES2 (0.59) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL9339370 | 0.80 | SMN1; SMN2 (0.53) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL12649365 | 0.78 | KMT2A (0.59) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL17383940 | 0.78 | KMT2A (0.59) | KMT2ATDP1MAPTMEN1PARP10 | |
| SCHEMBL9339364 | 0.78 | KMT2A (0.56) | KMT2ATDP1MAPTMEN1CES2 | |
| SCHEMBL11039744 | 0.78 | PARP10 (0.55) | KMT2ATDP1MAPTMEN1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288871-A | Modify balance between rates of bone resorption and formation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |