Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616356 | 0.89 | CES2 (0.59) | MAPTSMN1; SMN2PARP10CES2CES1 | |
| SCHEMBL11775909 | 0.88 | PARP10 (0.61) | MAPTSMN1; SMN2PARP10KMT2AALDH1A1 | |
| SCHEMBL8983809 | 0.83 | CES2 (0.59) | MAPTSMN1; SMN2PARP10CES2CES1 | |
| SCHEMBL9806487 | 0.82 | ELANE (0.58) | MAPTSMN1; SMN2PARP10KMT2AALDH1A1 | |
| SCHEMBL9806485 | 0.82 | PARP10 (0.54) | MAPTSMN1; SMN2PARP10KMT2AALDH1A1 | |
| SCHEMBL14725833 | 0.81 | MAPT (0.69) | MAPTSMN1; SMN2PARP10KMT2AALDH1A1 | |
| SCHEMBL12123501 | 0.81 | MAPT (0.72) | MAPTSMN1; SMN2PARP10KMT2AALDH1A1 | |
| SCHEMBL9528723 | 0.81 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2PARP10KMT2AALDH1A1 | |
| SCHEMBL26039005 | 0.79 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2PARP10KMT2AALDH1A1 | |
| SCHEMBL12199954 | 0.79 | MAPT (0.55) | MAPTSMN1; SMN2KMT2AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005173-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | AGOURON PHARMACEUTICALS, INC. (US) | 1992-04-02 | — | — | WO | disclosed |