Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12016522 | 0.85 | OPRD1 (0.70) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL4576626 | 0.82 | CYP3A4 (0.70) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL12017980 | 0.81 | CYP3A4 (0.79) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL4577073 | 0.81 | CYP3A4 (0.79) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL7623262 | 0.81 | MGLL (0.35) | OPRD1CYP3A4CYP2D6NFKB1 | |
| SCHEMBL7616416 | 0.80 | OPRD1 (0.63) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 | |
| SCHEMBL6933062 | 0.80 | OPRD1 (0.63) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 | |
| SCHEMBL8530182 | 0.80 | OPRD1 (0.63) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 | |
| SCHEMBL6933683 | 0.80 | OPRD1 (0.63) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 | |
| SCHEMBL6933065 | 0.80 | OPRD1 (0.63) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052007-A1 | Diarylmethylbenzylpiperazines and corresponding halobenzyl derivatives | ENTA HOLDING LLC | 2002-05-02 | — | — | US | disclosed |