SCHEMBL761658

SCHEMBL761658

CN1C(=O)C2CCCCC2C1=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 1/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
HTT P42858 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
APP P05067 1/20 0.34
BACE1 P56817 1/20 0.34
BACE2 Q9Y5Z0 1/20 0.34
ACHE P22303 1/20 0.34
PPOX P50336 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13239527 1.00 ALDH1A1 (0.41) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL13206576 1.00 ALDH1A1 (0.41) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL18626035 0.97 ALDH1A1 (0.39) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL21389157 0.97 ALDH1A1 (0.39) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL24763261 0.97 ALDH1A1 (0.39) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL23422468 0.94 MAPK1 (0.41) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL12552817 0.94 MAPK1 (0.41) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL23379740 0.92 MAPK1 (0.39) ALDH1A1MAPK1PDE4APDE4BPDE4C
SCHEMBL23379624 0.88 ACHE (0.36) ALDH1A1MAPK1ACHE
SCHEMBL22016051 0.88 ACHE (0.36) ALDH1A1MAPK1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP claimed
US-20230303578-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE (BEIJING) CO., LTD. (CN) 2023-09-28 US claimed
EP-4206205-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND Primegene (Beijing) Co., Ltd. (CN) 2023-07-05 EP claimed
EP-0885214-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS Cytec Technology Corp. (US) 1998-12-23 EP claimed
WO-1997031914-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1997-09-04 WO claimed
US-5006621-A Co-polymers of long chain alkyl acrylates with N-containing olefins and their use as flow improvers for crude oils HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-04-09 US claimed
EP-0334155-A1 Copolymers of long-chain alkyl acrylates with n-containing olefins, process for their preparation and their use as flow improvers in crude oils Henkel Kommanditgesellschaft auf Aktien (DE) 1989-09-27 EP claimed
US-4647625-A Process for modifying conjugated diene polymers NIPPON ZEON CO., LTD. (JP) 1987-03-03 US claimed
JP-8104781-A None JP disclosed
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
US-11780946-B2 Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-10 US disclosed
US-11780946-B2 Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-10 US disclosed
US-4225505-A Pyrolysis of N-substituted-1-cyclohexene-1,2-dicarboximides and hydrolysis of product to pyromellitic anhydride PHILLIPS PETROLEUM COMPANY (US) 1980-09-30 US disclosed
US-4193924-A Pyrolysis of N-substituted-1-cyclohexene-1,2-dicarboximides PHILLIPS PETROLEUM COMPANY (US) 1980-03-18 US disclosed
US-4163014-A 3,4,5,6-Tetrahydropyromellitdiimides PHILLIPS PETROLEUM COMPANY (US) 1979-07-31 US disclosed
US-4125536-A Pyrolysis product of N-substituted-1-cyclohexene-1,2-dicarboximides PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed
US-4056542-A Pyrolysis of N-substituted-1-cyclohexene-1,2-dicarboximides PHILLIPS PETROLEUM COMPANY (US) 1977-11-01 US disclosed
US-3932457-A Pyrolysis of N-substituted-1-cyclohexene-1,2-dicarboximides PHILLIPS PETROLEUM COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303578-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND DPYD, RPLP2, DHPS ALDH1A1 1717/4885MAPK1 2606/4885PDE4A 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.