SCHEMBL761659

SCHEMBL761659

CNc1ccc(Oc2ccc(NC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
APP P05067 2/20 0.45
ALDH1A1 P00352 5/20 0.44
HPGD P15428 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
CYP3A4 P08684 3/20 0.44
HTT P42858 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX12 P18054 1/20 0.44
CYP2C19 P33261 1/20 0.44
LMNA P02545 1/20 0.44
PGR P06401 1/20 0.43
GAA P10253 3/20 0.43
MAPT P10636 2/20 0.43
RECQL P46063 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
THRB P10828 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15339364 1.00 TSHR (0.48) TSHRAPPALDH1A1HPGDSMN1; SMN2
SCHEMBL3686642 0.90 TSHR (0.59) TSHRALDH1A1HPGDSMN1; SMN2HTT
SCHEMBL13107871 0.90 MAPT (0.58) APPALDH1A1HPGDSMN1; SMN2HTT
SCHEMBL13788782 0.90 TEAD4 (0.54) TSHRALDH1A1HPGDSMN1; SMN2HTT
SCHEMBL1108591 0.88 MAOA (0.52) ALDH1A1PGRL3MBTL1CA2
SCHEMBL19601222 0.88 APP (0.43) TSHRAPPALDH1A1HPGDSMN1; SMN2
SCHEMBL11706736 0.88 ALDH1A1 (0.64) TSHRALDH1A1HPGDSMN1; SMN2CYP3A4
SCHEMBL3022633 0.88 FFAR1 (0.46) APP
SCHEMBL171930 0.86 SCN9A (0.47) SMN1; SMN2LMNAGAAMAPTTDP1
Hydrochloric Acid SCHEMBL6405592 0.86 FFAR1 (0.45) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179028-A1 SOLVENT RESISTANT PHOTOSENSITIVE COMPOSITIONS Syntrix Biochip, Inc. (US) 2002-02-13 EP claimed
WO-2000032678-A1 SOLVENT RESISTANT PHOTOSENSITIVE COMPOSITIONS SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO claimed
CN-119931728-A High-octane gasoline antiknock agent 山东信手天来生物科技有限公司 2025-05-06 CN disclosed
US-20210120817-A1 PLANT DISEASE CONTROL AGENT MEIJI SEIKA PHARMA CO., LTD. (JP) 2021-04-29 US disclosed
US-10947345-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2021-03-16 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20170141372-A1 POROUS LAYER FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SEPARATOR, AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY LAMINATED SEPARATOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 US disclosed
US-8936840-B2 Retardation film, polarizing plate, liquid crystal display device, and compound Konica Minolta, Inc. (JP) 2015-01-20 US disclosed
US-8936840-B2 Retardation film, polarizing plate, liquid crystal display device, and compound Konica Minolta, Inc. (JP) 2015-01-20 US disclosed
US-8658757-B2 Polyamide polymer, method for producing same, resin composition, molded product, fiber, film, and porous film FUJIFILM CORPORATION (JP) 2014-02-25 US disclosed
US-5004774-A Heat resistance, shrinkage inhibition LUCKY, LTD. (KR) 1991-04-02 US disclosed
US-4275184-A HYDROSILATION OF POLYDIMETHYL SILOXANE RHONE-POULENC INDUSTRIES (FR) 1981-06-23 US disclosed
US-4213914-A ADDITION-CONDENSATION COPOLYMERS RHONE-POULENC INDUSTRIES (FR) 1980-07-22 US disclosed
US-4147711-A Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom RHONE-POULENC INDUSTRIES (FR) 1979-04-03 US disclosed
US-4140658-A Cyanamides of secondary amines as epoxy curing agents CIBA-GEIGY CORPORATION (US) 1979-02-20 US disclosed
US-4088670-A P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID RHONE-POULENC INDUSTRIES (FR) 1978-05-09 US disclosed
US-4057518-A Process for the manufacture of heat resistant multicellular materials RHONE-POULENC INDUSTRIES (FR) 1977-11-08 US disclosed
US-4013600-A STORAGE STABILITY RHONE-POULENC INDUSTRIES (FR) 1977-03-22 US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210120817-A1 PLANT DISEASE CONTROL AGENT BROX, ALG1, CTRL TSHR 4374/4885APP 3564/4885ALDH1A1 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.