Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618333 | 1.00 | LMNA (0.47) | LMNATBXAS1ALDH1A1GAAHSD17B10 | |
| SCHEMBL7623134 | 0.99 | LMNA (0.45) | LMNATBXAS1ALDH1A1GAAHSD17B10 | |
| SCHEMBL7620248 | 0.84 | HPGD (0.43) | LMNATBXAS1ALDH1A1HPGDPDE3B | |
| SCHEMBL7623365 | 0.82 | TSHR (0.42) | LMNATBXAS1ALDH1A1HSD17B10HPGD | |
| SCHEMBL7623376 | 0.82 | CYP4F2 (0.46) | TBXAS1ALDH1A1HSD17B10MAPTALOX15 | |
| SCHEMBL7621113 | 0.80 | CYP4F2 (0.47) | TBXAS1ALDH1A1HSD17B10MAPTALOX15 | |
| SCHEMBL4873532 | 0.80 | TSHR (0.42) | LMNATBXAS1ALDH1A1HSD17B10HPGD | |
| SCHEMBL7623156 | 0.78 | MEN1 (0.47) | TBXAS1ALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL7621282 | 0.78 | TBXAS1 (0.38) | TBXAS1 | |
| SCHEMBL7622667 | 0.78 | MEN1 (0.47) | TBXAS1ALDH1A1GAAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |