Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623376 | 0.99 | CYP4F2 (0.46) | CYP4F2CYP4A11ALDH1A1CYP3A4TDP1 | |
| SCHEMBL7613936 | 0.97 | CYP3A4 (0.45) | CYP4F2CYP4A11ALDH1A1CYP3A4TDP1 | |
| SCHEMBL7623365 | 0.85 | TSHR (0.42) | ALDH1A1TSHRHSD17B10SMN1; SMN2TBXAS1 | |
| SCHEMBL4873532 | 0.82 | TSHR (0.42) | ALDH1A1TSHRHSD17B10TBXAS1MAPT | |
| SCHEMBL7623134 | 0.81 | LMNA (0.45) | ALDH1A1ALOX15TSHRHSD17B10TBXAS1 | |
| SCHEMBL7616683 | 0.80 | LMNA (0.47) | ALDH1A1ALOX15TSHRHSD17B10TBXAS1 | |
| SCHEMBL7618333 | 0.80 | LMNA (0.47) | ALDH1A1ALOX15TSHRHSD17B10TBXAS1 | |
| SCHEMBL7616487 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL9114807 | 0.78 | TBXAS1 (0.64) | CYP4F2CYP4A11ALDH1A1CYP3A4TDP1 | |
| SCHEMBL7623524 | 0.78 | TBXAS1 (0.58) | ALDH1A1TSHRCYP1A2CYP2C19TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |