Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22535911 | 0.87 | NAALAD2 (0.46) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL7527191 | 0.76 | LMNA (0.36) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL2203104 | 0.75 | FFAR1 (0.65) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL9580919 | 0.73 | HMGCR (0.67) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL12745311 | 0.72 | NAALAD2 (0.46) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL27651457 | 0.72 | NAALAD2 (0.46) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL9805711 | 0.71 | ALDH1A1 (0.43) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL6061318 | 0.71 | ALDH1A1 (0.48) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL27539128 | 0.71 | HIF1A (0.68) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL10577709 | 0.71 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436136-B1 | Shaped bodies for use as implants in human medicine and method for the production of such shaped bodies | ARTIMPLANT AB (SE) | 2002-08-20 | — | — | US | claimed |
| US-6436136-B1 | Shaped bodies for use as implants in human medicine and method for the production of such shaped bodies | ARTIMPLANT AB (SE) | 2002-08-20 | — | — | US | disclosed |
| EP-1027086-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | Artimplant AB (SE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999022780-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | ARTIMPLANT AB (SE) | 1999-05-14 | — | — | WO | disclosed |