SCHEMBL7527191

SCHEMBL7527191

O=C(O)CCC(CC(=O)O)(CC(=O)O)C(CO)(CO)CO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
CAMK2A Q9UQM7 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
THRB P10828 1/20 0.34
KMT2A Q03164 1/20 0.34
FFAR1 O14842 2/20 0.33
CPT2 P23786 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
NAALAD2 Q9Y3Q0 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2401741 0.82 ALDH1A1 (0.41) LMNAALKBH5SUCNR1EGLN1ALDH1A1
SCHEMBL7616709 0.76 HMGCR (0.44) LMNAALKBH5SUCNR1EGLN1ALDH1A1
SCHEMBL540504 0.73 ALDH1A1 (0.35) CAMK2AALDH1A1FFAR1CPT2HMGCR
SCHEMBL15703329 0.73 CAMK2A (0.42) LMNAALKBH5SUCNR1EGLN1CAMK2A
SCHEMBL2402628 0.73 CAMK2A (0.48) LMNAALKBH5SUCNR1EGLN1CAMK2A
SCHEMBL9805711 0.71 ALDH1A1 (0.43) LMNAALKBH5SUCNR1EGLN1ALDH1A1
SCHEMBL11857314 0.70 TSHR (0.55) LMNACAMK2AALDH1A1MEN1THRB
SCHEMBL5138772 0.69 LMNA (0.44) LMNAALKBH5SUCNR1EGLN1CAMK2A
SCHEMBL1311882 0.69 LMNA (0.44) LMNAALKBH5SUCNR1EGLN1CAMK2A
SCHEMBL31130665 0.69 LMNA (0.44) LMNAALKBH5SUCNR1EGLN1CAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1027086-B1 SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES ARTIMPLANT AB (SE) 2002-04-17 EP claimed
US-6436136-B1 Shaped bodies for use as implants in human medicine and method for the production of such shaped bodies ARTIMPLANT AB (SE) 2002-08-20 US disclosed
EP-1027086-B1 SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES ARTIMPLANT AB (SE) 2002-04-17 EP disclosed
EP-1027086-A1 SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES Artimplant AB (SE) 2000-08-16 EP disclosed
WO-1999022780-A1 SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES ARTIMPLANT AB (SE) 1999-05-14 WO disclosed