Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379817 | 0.81 | GABRA1 (0.38) | GABRA1GABRB2ELANE | |
| SCHEMBL10767160 | 0.79 | HIF1A (0.34) | — | |
| SCHEMBL4737660 | 0.78 | — | — | |
| SCHEMBL1828031 | 0.78 | DAO (0.33) | — | |
| SCHEMBL7213697 | 0.77 | — | — | |
| SCHEMBL2526583 | 0.74 | LIPG (0.39) | — | |
| SCHEMBL2158571 | 0.72 | SLC6A4 (0.36) | — | |
| SCHEMBL23733959 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2 | |
| SCHEMBL7716433 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2GABRG2GABRB3GABRA2 | |
| SCHEMBL29410060 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2GABRG2GABRB3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |