Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4658126 | 0.88 | NPC1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL31571612 | 0.88 | NPC1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL1009752 | 0.87 | KDM4E (0.32) | — | |
| Hydrochloric Acid SCHEMBL29934113 | 0.87 | KDM4E (0.32) | — | |
| Hydrochloric Acid SCHEMBL7618718 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL31126405 | 0.85 | KDM4E (0.32) | — | |
| Hydrochloric Acid SCHEMBL31571589 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL31571615 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL8571945 | 0.84 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL7620253 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834519-B1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | JAPAN POLYOLEFINS CO LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6121182-A | A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES | JAPAN POLYOLAFINS CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0834519-A1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | Japan Polyolefins Co., Ltd. (JP) | 1998-04-08 | — | — | EP | disclosed |