Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29934113 | 1.00 | KDM4E (0.32) | KDM4EKDM1ACA12CA1CA2 | |
| Fluoride Ion SCHEMBL31126405 | 0.97 | KDM4E (0.32) | KDM4EKDM1ACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8571945 | 0.96 | KDM4E (0.30) | KDM4EKDM1ACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL629191 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL3814873 | 0.89 | ALDH1A1 (0.34) | ALDH1A1HPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7643024 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7617009 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL338847 | 0.86 | KDM4E (0.37) | KDM4EKDM1AALDH1A1CYP2A6SLC6A4 | |
| Hydrochloric Acid SCHEMBL3807132 | 0.86 | CES1 (0.33) | ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3123293 | 0.86 | ALDH1A1 (0.32) | ALDH1A1HPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088836-B1 | ETHYLENE/ALPHA-OLEFIN/UNCONJUGATED POLYENE COPOLYMER RUBBER, RUBBER COMPOSITION FOR SEALING, MOLDED RUBBER FOR SEALING, AND PROCESS FOR PRODUCING THE MOLDED RUBBER PART | MITSUI CHEMICALS INC (JP) | 2012-11-21 | — | — | EP | disclosed |
| EP-1995037-B1 | PROCESS FOR PRODUCTION OF MOLDINGS BY THE INFLATION METHOD | MITSUI CHEMICALS INC (JP) | 2011-07-06 | — | — | EP | disclosed |
| US-7943120-B2 | Olefin wax, silicone-modified olefin wax, silicone-modified room temperature-solidifying composition using the wax, and cosmetics using them | MITSUI CHEMICALS, INC. (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-1953185-B1 | METHOD FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION | MITSUI CHEMICALS INC (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-1944338-B1 | PROCESS FOR PRODUCTION OF THERMOPLASTIC RESIN COMPOSITION | MITSUI CHEMICALS INC (JP) | 2010-01-13 | — | — | EP | disclosed |
| EP-1408078-B1 | Resin composition comprising a linear ethylene/alpha-olefin-copolymer and a long-chain branched ethylene/alpha-olefin-copolymer and films of the same | MITSUI CHEMICALS INC (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-20090137729-A1 | Process for Producing Oriented Film | MITSUI CHEMICALS, INC. (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2002963-A9 | PROCESS FOR PRODUCING ORIENTED FILM | Mitsui Chemicals, Inc. (JP) | 2009-04-22 | — | — | EP | disclosed |
| US-20090081151-A1 | Olefin wax, silicone-modified olefin wax, silicone-modified room temperature-solidifying composition using the wax, and cosmetics using them | MITSUI CHEMICALS, INC. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-2002963-A2 | PROCESS FOR PRODUCING ORIENTED FILM | Mitsui Chemicals, Inc. (JP) | 2008-12-17 | — | — | EP | disclosed |
| EP-0707016-B1 | Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst | JAPAN POLYOLEFINS CO LTD (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0791626-A1 | RESIN COMPOSITIONS AND USE THEREOF | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-27 | — | — | EP | disclosed |
| EP-0781788-A2 | Unsaturated copolymer based on olefin and production and use thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0763553-A1 | PROCESS FOR PREPARING OLEFIN POLYMER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-19 | — | — | EP | disclosed |
| EP-0754731-A2 | Polyamide resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0751182-A1 | Olefin thermoplastic elastomer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0751156-A2 | Ethylene copolymer rubber, vulcanizable rubber composition containing the copolymer rubber, and process for preparing the copolymer rubber | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0707016-A1 | Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst | JAPAN POLYOLEFINS CO., LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0691354-A1 | Unsaturated copolymer of ethylene and process for preparing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| EP-0682042-A1 | PROPYLENE ELASTOMER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090081151-A1 | Olefin wax, silicone-modified olefin wax, silicone-modified room temperature-solidifying composition using the wax, and cosmetics using them | CUTA, OR10J3, MSH6 | SLC6A2 4747/4885SLC6A3 4831/4885KDM4E 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.