Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1009752 | 1.00 | KDM4E (0.32) | KDM4EKDM1ACA12CA1CA2 | |
| Fluoride Ion SCHEMBL31126405 | 0.97 | KDM4E (0.32) | KDM4EKDM1ACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8571945 | 0.96 | KDM4E (0.30) | KDM4EKDM1ACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL629191 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL3814873 | 0.89 | ALDH1A1 (0.34) | ALDH1A1HPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7643024 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7617009 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL338847 | 0.86 | KDM4E (0.37) | KDM4EKDM1AALDH1A1CYP2A6SLC6A4 | |
| Hydrochloric Acid SCHEMBL3807132 | 0.86 | CES1 (0.33) | ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3123293 | 0.86 | ALDH1A1 (0.32) | ALDH1A1HPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946309-A | Polymerization method of polybutene-1 and preparation method of polybutene-1 resin | 中国石油化工股份有限公司 | 2024-04-30 | — | — | CN | disclosed |