Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615538 | 1.00 | CEL (0.36) | CELCYP1A2SIGMAR1HRH3GPR84 | |
| SCHEMBL7620235 | 0.98 | HRH3 (0.36) | CELCYP1A2SIGMAR1HRH3GPR84 | |
| SCHEMBL7625870 | 0.95 | HRH3 (0.36) | CELHRH3 | |
| SCHEMBL7624059 | 0.92 | HRH3 (0.37) | HRH3 | |
| SCHEMBL7617332 | 0.90 | DAO (0.38) | CELHRH3DAOHRH4 | |
| SCHEMBL6208066 | 0.90 | DAO (0.38) | CELHRH3DAOHRH4 | |
| SCHEMBL7625880 | 0.81 | HRH3 (0.34) | HRH3DAO | |
| SCHEMBL7621930 | 0.80 | HRH4 (0.43) | HRH3DAOHRH4 | |
| SCHEMBL7620211 | 0.80 | HRH4 (0.43) | HRH3DAOHRH4 | |
| SCHEMBL30578654 | 0.75 | TBXAS1 (0.44) | CELCYP1A2SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |