SCHEMBL7625880

SCHEMBL7625880

[c]1c[nH]c(CCC2CC2)n1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.34
DAO P14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6208066 0.91 DAO (0.38) HRH3DAO
SCHEMBL7617332 0.91 DAO (0.38) HRH3DAO
SCHEMBL7624059 0.89 HRH3 (0.37) HRH3
SCHEMBL7625870 0.82 HRH3 (0.36) HRH3
SCHEMBL7620235 0.82 HRH3 (0.36) HRH3DAO
SCHEMBL7615538 0.81 CEL (0.36) HRH3DAO
SCHEMBL7617060 0.81 CEL (0.36) HRH3DAO
SCHEMBL7621930 0.72 HRH4 (0.43) HRH3DAO
SCHEMBL7620211 0.72 HRH4 (0.43) HRH3DAO
SCHEMBL1705486 0.71 TERT (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1232166-A2 SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES Pharmasset Limited (US) 2002-08-21 EP disclosed
WO-2001034618-A2 SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES PHARMASSET LIMITED (US) 2001-05-17 WO disclosed
US-5594003-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-14 US disclosed