SCHEMBL7617282

SCHEMBL7617282

CCCCN(CCCC)CCCNC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 4/20 0.47
ALDH1A1 P00352 2/20 0.47
PHF8 Q9UPP1 2/20 0.45
KDM4C Q9H3R0 2/20 0.45
DNM1 Q05193 1/20 0.44
EPHX1 P07099 5/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD3 P35462 1/20 0.42
NAAA Q02083 1/20 0.41
GAA P10253 1/20 0.41
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18074396 1.00 KDM5A (0.47) KDM5AALDH1A1PHF8KDM4CDNM1
SCHEMBL17848972 0.92 ALDH1A1 (0.49) KDM5AALDH1A1PHF8KDM4CDNM1
SCHEMBL11146017 0.92 DRD2 (0.49) KDM5AALDH1A1PHF8KDM4CDNM1
SCHEMBL4157740 0.92 ALDH1A1 (0.49) KDM5AALDH1A1PHF8KDM4CDNM1
SCHEMBL15570032 0.89 CA12 (0.43) KDM5AALDH1A1PHF8KDM4CDNM1
SCHEMBL20589935 0.88 EPHX1 (0.55) KDM5APHF8KDM4CDNM1EPHX1
SCHEMBL20548058 0.87 NAAA (0.47) KDM5AALDH1A1PHF8KDM4CDNM1
SCHEMBL28075681 0.86 DRD2 (0.55) KDM5AALDH1A1PHF8KDM4CEPHX1
SCHEMBL21525430 0.85 EPHX1 (0.61) KDM5AALDH1A1DNM1EPHX1CA12
SCHEMBL17415969 0.85 ALDH1A1 (0.62) ALDH1A1KDM4ELMNAKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885239-B1 NOVEL STEROID CARBAMATES AS POTENTIATING AGENTS BATRA SATISH (SE) 2002-08-07 EP claimed
US-5480989-A Carbamates of rapamycin AMERICAN HOME PRODUCTS CORPORATION (US) 1996-01-02 US claimed
EP-0885239-B1 NOVEL STEROID CARBAMATES AS POTENTIATING AGENTS BATRA SATISH (SE) 2002-08-07 EP disclosed
US-6046182-A Steroid carbamates as potentiating agents SATISH BATRA (SE) 2000-04-04 US disclosed
US-6046182-A Steroid carbamates as potentiating agents SATISH BATRA (SE) 2000-04-04 US disclosed
EP-0885239-A1 NOVEL STEROID CARBAMATES AS POTENTIATING AGENTS Batra, Satish (SE) 1998-12-23 EP disclosed
WO-1997027211-A1 NOVEL STEROID CARBAMATES AS POTENTIATING AGENTS BATRA SATISH (SE) 1997-07-31 WO disclosed
US-5559120-A IMMUNOSUPPRESSANTS, ANTIINFLAMMATORY AGENTS, FUNGICIDES AND ANTITUMOR AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-09-24 US disclosed
US-5530121-A IMMUNOSUPPRESSANTS, ANTIINFLAMMATORY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-06-25 US disclosed
US-5530007-A ANTITUMOR, ANTIINFLAMMATORY, ANTIFUNGAL, ANTIPROLIFERATIVE, IMMUNOSUPPRESSIVE AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-06-25 US disclosed
US-5508399-A USEFUL AS IMMUNOSUPPRESSANT, ANTIINFLAMMATORY, ANTIFUNGAL, ANTIPROLIFERATIVE AND ANTIUMOR AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-04-16 US disclosed
US-5480989-A Carbamates of rapamycin AMERICAN HOME PRODUCTS CORPORATION (US) 1996-01-02 US disclosed