Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230550 | 0.89 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL2166946 | 0.86 | TDP1 (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8899641 | 0.82 | TDP1 (0.50) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL339522 | 0.82 | TSHR (0.53) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL2167795 | 0.79 | TDP1 (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8899918 | 0.79 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL229200 | 0.79 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL16537584 | 0.78 | TSHR (0.56) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL230778 | 0.77 | TDP1 (0.50) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL16537639 | 0.77 | TSHR (0.58) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230273-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | Bridgestone Corporation (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034658-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | BRIDGESTONE CORPORATION (JP) | 2001-05-17 | — | — | WO | disclosed |