SCHEMBL2166946

SCHEMBL2166946

C=C(C)C(=O)OCCC[Si](CC)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
ELANE P08246 1/20 0.37
RECQL P46063 1/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 2/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8899641 0.93 TDP1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL2167795 0.87 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR
SCHEMBL7617869 0.86 TDP1 (0.40) TDP1POLBAPEX1HTTTSHR
SCHEMBL230778 0.85 TDP1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL230550 0.84 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL229200 0.84 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL8899918 0.84 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL1063223 0.82 THRB (0.54) TDP1TSHRTHRBL3MBTL1RECQL
SCHEMBL230780 0.78 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL2166950 0.78 ATM (0.37) TDP1THRBL3MBTL1RECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-20140206801-A1 INORGANIC OXIDE TRANSPARENT DISPERSION, RESIN COMPOSITION USED TO FORM TRANSPARENT COMPOSITE, TRANSPARENT COMPOSITE, AND OPTICAL MEMBER SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2014-07-24 US disclosed
EP-2752392-A1 INORGANIC OXIDE TRANSPARENT DISPERSION AND RESIN COMPOSITION FOR FORMING TRANSPARENT COMPOSITE, AND TRANSPARENT COMPOSITE AND OPTICAL MEMBER Sumitomo Osaka Cement Co., Ltd. (JP) 2014-07-09 EP disclosed
US-7985476-B2 Transparent zirconia dispersion and zirconia particle-containing resin composition, composition for sealing light emitting element and light emitting element, hard coat film and optical functional film and optical component, and method for producing zirconia particle-containing resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2011-07-26 US disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed