SCHEMBL230778

SCHEMBL230778

C=C(C)C(=O)OCCC[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TSHR P16473 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.40
ELANE P08246 1/20 0.39
THRB P10828 2/20 0.38
MTNR1A P48039 2/20 0.38
MTNR1B P49286 2/20 0.38
RECQL P46063 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8899641 0.89 TDP1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL229200 0.87 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL230550 0.87 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL8899918 0.87 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL2167795 0.85 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR
SCHEMBL2166946 0.85 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR
SCHEMBL12195017 0.84 POLB (0.46) TDP1POLBAPEX1HTTTSHR
SCHEMBL230468 0.82 ELANE (0.43) TDP1POLBAPEX1HTTTSHR
SCHEMBL230780 0.82 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL13579532 0.81 TDP1 (0.48) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7750087-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-07-06 US claimed
US-20060030677-A1 Prepared by polymerizing conjugated monomer with a lanthanide-based catalyst to form a pseudo-living polymer and reacting the polymer with a di- or trihydrocarbyloxysilane having a reactive functional group such as (meth)acrylate, epoxy, or isocyanate that forms a chemical bond with the polymer; curable ENEOS MATERIALS CORPORATION (JP) 2006-02-09 US claimed
US-6992147-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2006-01-31 US claimed
EP-3257685-B1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR MANUFACTURING SAME, AND PRINTING METHOD USING SAME FUJIFILM CORP (JP) 2020-03-04 EP disclosed
US-10022998-B2 Planographic printing plate precursor, method of producing same, and printing method using same FUJIFILM CORPORATION (JP) 2018-07-17 US disclosed
EP-3257685-A1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR MANUFACTURING SAME, AND PRINTING METHOD USING SAME Fujifilm Corporation (JP) 2017-12-20 EP disclosed
US-20170320350-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND PRINTING METHOD USING SAME FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-9593234-B2 Rubber composition having intramolecular double bond THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-03-14 US disclosed
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-20150329708-A1 RUBBER COMPOSITION HAVING INTRAMOLECULAR DOUBLE BOND THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-11-19 US disclosed
US-8934165-B2 Electrophoretic particle, manufacturing method of electrophoretic particle, electrophoretic dispersed liquid, electrophoretic sheet, electrophoretic apparatus, and electronic equipment SEIKO EPSON CORPORATION (JP) 2015-01-13 US disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed
EP-1230273-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-08-14 EP disclosed
WO-2001034658-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TDP1 4205/4885POLB 2487/4885APEX1 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.