Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622667 | 1.00 | MEN1 (0.47) | MEN1FAAHMAPK1KMT2AALDH1A1 | |
| SCHEMBL7623156 | 1.00 | MEN1 (0.47) | MEN1FAAHMAPK1KMT2AALDH1A1 | |
| SCHEMBL7618079 | 0.84 | TBXAS1 (0.41) | FAAHTBXAS1HDAC3HDAC4HDAC1 | |
| SCHEMBL7617067 | 0.81 | VHL (0.41) | MEN1FAAHMAPK1KMT2AALDH1A1 | |
| SCHEMBL7625860 | 0.80 | CNR1 (0.43) | MEN1FAAHKMT2AALDH1A1HPGD | |
| SCHEMBL7621282 | 0.78 | TBXAS1 (0.38) | TBXAS1 | |
| SCHEMBL7616683 | 0.78 | LMNA (0.47) | MAPK1ALDH1A1KDM4ETBXAS1HPGD | |
| SCHEMBL7618333 | 0.78 | LMNA (0.47) | MAPK1ALDH1A1KDM4ETBXAS1HPGD | |
| SCHEMBL7621773 | 0.77 | TBXAS1 (0.61) | TBXAS1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7614088 | 0.77 | TBXAS1 (0.61) | TBXAS1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |