Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | PTGIR | P43119 | 1/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616619 | 0.81 | PGR (0.34) | PTGFRPTGER2TBXA2R | |
| SCHEMBL18022087 | 0.68 | PTGFR (0.41) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL8822932 | 0.67 | MEN1 (0.42) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL8822856 | 0.67 | MEN1 (0.42) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL18022086 | 0.66 | PTGFR (0.53) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL18023370 | 0.66 | PTGFR (0.39) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL17460690 | 0.66 | PTGFR (0.42) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL11912319 | 0.65 | PTGFR (0.38) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL3009597 | 0.65 | PTGFR (0.38) | PTGFRPTGER2TBXA2RPTGER1PTGDR | |
| SCHEMBL14352897 | 0.65 | PTGFR (0.38) | PTGFRPTGER2TBXA2RPTGER1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452039-B1 | PROSTANOIC ACID DERIVATIVE WHEREIN THE ALPHA CHAIN HAS EIGHT OR MORE SKELETAL CARBON ATOMS; EXTREMELY STRONG ACTION; HYPERTENSION, ASTHMA, DIABETES, ARTERIAL SCLEROSIS, RENAL FAILURE, CARDIAC INFARCTION, ANGINA PECTORIS | SUCAMPO AG (CH) | 2002-09-17 | — | — | US | disclosed |
| EP-0857718-B1 | ENDOTHELIN ANTAGONIST | SUCAMPO AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| US-6242485-B1 | ADMINISTERING PROSTANOIC ACID DERIVATIVE TO TREAT VISION, KIDNEY, CARDIOVASCULAR AND BRAIN DISORDERS; HYPOTENSIVE AND ANTIASTHMATIC AGENTS | R-TECH UENO (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0857718-A1 | ENDOTHELIN ANTAGONIST | R-Tech Ueno, Ltd. (JP) | 1998-08-12 | — | — | EP | disclosed |