SCHEMBL7618702

SCHEMBL7618702

O=S(=O)(SOSS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.48
PTPN5 P54829 1/20 0.48
PTPN11 Q06124 1/20 0.48
HTR6 P50406 2/20 0.48
ALDH1A1 P00352 3/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
HSD17B10 Q99714 1/20 0.44
CA12 O43570 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
PLA2G7 Q13093 1/20 0.44
CA9 Q16790 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11323690 0.76 HTR6 (0.55) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL565121 0.76 HTR6 (0.55) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL28841908 0.72 ALDH1A1 (0.52) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL5166440 0.72 HTR6 (0.50) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL15434593 0.72 HTR6 (0.50) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL11335316 0.72 HTR6 (0.50) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL31452871 0.70 HTR6 (0.55) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL576427 0.70 HTR6 (0.55) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL31452872 0.70 HTR6 (0.55) DUSP3PTPN5PTPN11HTR6ALDH1A1
SCHEMBL135257 0.70 DNMT1 (0.56) DUSP3PTPN5PTPN11HTR6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103113387-B The synthetic method of asymmetric two thieno-heteroaromatic compounds HENAN UNIVERSITY (CN) 2016-02-17 CN claimed
CN-103113387-B The synthetic method of asymmetric two thieno-heteroaromatic compounds HENAN UNIVERSITY (CN) 2016-02-17 CN disclosed
CN-103113387-B The synthetic method of asymmetric two thieno-heteroaromatic compounds HENAN UNIVERSITY (CN) 2016-02-17 CN disclosed
CN-103113387-A Synthesis method of asymmetrical dithieno heteroaromatic compounds UNIV HENAN 2013-05-22 CN disclosed
CN-103113387-A Synthesis method of asymmetrical dithieno heteroaromatic compounds UNIV HENAN 2013-05-22 CN disclosed
EP-0880540-B1 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE AVENTIS PHARMA INC (US) 2002-06-12 EP disclosed
US-6365597-B1 FOR THERAPY OF ANDROGEN AND ESTROGEN MEDIATED DISORDERS, INCLUDING BENIGN PROSTATIC HYPERPLASIA, ANDROGEN MEDIATED PROSTATE CANCER, ESTROGEN MEDIATED BREAST CANCER AND ACNE AVENTIS PHARMACEUTICALS INC. 2002-04-02 US disclosed
EP-0880540-A1 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE HOECHST MARION ROUSSEL, INC. (US) 1998-12-02 EP disclosed
WO-1997030069-A1 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE HOECHST MARION ROUSSEL, INC. (US) 1997-08-21 WO disclosed