SCHEMBL5166440

SCHEMBL5166440

CSS(=O)(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.50
PSIP1 O75475 1/20 0.48
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
CA2 P00918 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CA1 P00915 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
PLA2G7 Q13093 1/20 0.46
CA9 Q16790 1/20 0.46
CA13 Q8N1Q1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27511361 0.97 HTR6 (0.48) HTR6PSIP1ALDH1A1KDM4ELMNA
SCHEMBL565121 0.78 HTR6 (0.55) HTR6PSIP1ALDH1A1KDM4ELMNA
SCHEMBL11323690 0.78 HTR6 (0.55) HTR6PSIP1ALDH1A1KDM4ELMNA
SCHEMBL7271430 0.77 DNMT1 (0.61) ALDH1A1MAPTCA2SMN1; SMN2CA1
SCHEMBL11293450 0.75 ALDH1A1 (0.54) ALDH1A1KDM4EMAPTCA2SMN1; SMN2
SCHEMBL15076023 0.75 CA2 (0.50) CA2CA1CA12CA9CA14
SCHEMBL11335316 0.74 HTR6 (0.50) HTR6PSIP1ALDH1A1KDM4ELMNA
SCHEMBL15434593 0.74 HTR6 (0.50) HTR6PSIP1ALDH1A1KDM4ELMNA
SCHEMBL28841908 0.74 ALDH1A1 (0.52) HTR6PSIP1ALDH1A1KDM4ELMNA
SCHEMBL11291589 0.73 PSIP1 (0.54) HTR6PSIP1ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN claimed
US-20240217913-A2 PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND HUA MEDICINE (SHANGHAI) LTD. (CN) 2024-07-04 US disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
EP-4219516-A2 CHIRAL CONTROL Wave Life Sciences Ltd. (SG) 2023-08-02 EP disclosed
EP-4137572-A1 CHIRAL DESIGN Wave Life Sciences Ltd. (SG) 2023-02-22 EP disclosed
EP-2872147-B1 METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES WAVE LIFE SCIENCES LTD (SG) 2022-12-21 EP disclosed
EP-3284599-B1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORP (JP) 2019-07-03 EP disclosed
US-20190106460-A1 BINDING INHIBITORS OF THE BETA. TRANSDUCIN REPEAT-CONTAINING PROTEIN BRADLEY MARK (GB) 2019-04-11 US disclosed
WO-2019055951-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2019-03-21 WO disclosed
EP-1218391-B1 COMPOUNDS FOR PROTECTING HYDROXYLS AND METHODS FOR THEIR USE HELICOS BIOSCIENCES CORP (US) 2007-04-11 EP disclosed
US-20040175726-A1 Compounds for protecting hydroxyls and methods for their use QUIATECH AB, A SWEDISH CORPORATION 2004-09-09 US disclosed
US-6639088-B2 Hydrocarbyldithiomethyl-modified compound; for use in chemically synthesizing oligonucleotides and for sequencing QUIATECH AB (SE) 2003-10-28 US disclosed
EP-1218391-A1 COMPOUNDS FOR PROTECTING HYDROXYLS AND METHODS FOR THEIR USE Quiatech AB (SE) 2002-07-03 EP disclosed
US-20020015961-A1 Compounds for protecting hydroxyls and methods for their use INTELLIGENT BIOSYSTEMS INC. 2002-02-07 US disclosed
US-6309836-B1 CONTACTING TARGET NUCLEIC ACID WITH PRIMER SO PRIMER ANNEALS TO NUCLEIC ACID IN SEQUENCE SPECIFIC MANNER, INCORPORATING HYDROCARBYLDITHIOMETHYL-MODIFIED NUCLEOTIDE INTO PRIMER, DETECTING MODIFIED NUCLEOTIDE, IDENTIFYING SEQUENCE OF BASE ILLUMINA, INC. 2001-10-30 US disclosed
WO-2001025247-A1 COMPOUNDS FOR PROTECTING HYDROXYLS AND METHODS FOR THEIR USE QUIATECH AB (SE) 2001-04-12 WO disclosed
US-4954518-A Antiinflammatory agents TOYAMA CHEMICAL COMPANY, LTD. (JP) 1990-09-04 US disclosed
EP-0019146-B1 COMBINATION OF FOAMING AGENTS BASED ON AZODICARBONAMIDE, ITS PREPARATION AND ITS USE FOR THE PREPARATION OF POROUS SYNTHETIC THERMOPLASTIC ARTICLES BAYER AG (DE) 1982-06-23 EP disclosed
US-4263165-A Blowing agent combination comprising azodicarbonamide, zinc oxide and a benzenethiol sulphonic acid derivative BAYER AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020015961-A1 Compounds for protecting hydroxyls and methods for their use NSUN2, OGG1, RNGTT HTR6 806/4885PSIP1 3346/4885ALDH1A1 179/4885
US-20240217913-A2 PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND ACR, ADCYAP1R1, GNPAT HTR6 866/4885PSIP1 2008/4885ALDH1A1 76/4885
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT HTR6 3520/4885PSIP1 915/4885ALDH1A1 3318/4885
US-20190106460-A1 BINDING INHIBITORS OF THE BETA. TRANSDUCIN REPEAT-CONTAINING PROTEIN TARDBP, DDB1, EPS15 HTR6 3728/4885PSIP1 3511/4885ALDH1A1 4636/4885
US-20040175726-A1 Compounds for protecting hydroxyls and methods for their use NSUN2, OGG1, RNGTT HTR6 806/4885PSIP1 3346/4885ALDH1A1 179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.