Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149190 | 0.76 | ITGB1 (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL7787321 | 0.74 | L3MBTL1 (0.37) | AKR1C4AKR1C3AKR1C2ALDH1A1POLB | |
| SCHEMBL6349829 | 0.73 | ITGB3 (0.33) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL8631434 | 0.64 | ITGB1 (0.48) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL28066720 | 0.63 | — | — | |
| SCHEMBL11042273 | 0.63 | ITGB3 (0.39) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL114053 | 0.62 | AKR1C4 (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL29954148 | 0.62 | ALDH1A1 (0.58) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL10248636 | 0.62 | ALDH1A1 (0.40) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL2559145 | 0.62 | ALDH1A1 (0.58) | ITGB1ITGA5ITGB3ITGB2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138224-B2 | Nutritional or therapeutic composition containing the compound oleuropeine or one of the derivatives thereof | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA) (FR) | 2012-03-20 | — | — | US | disclosed |
| US-8138224-B2 | Nutritional or therapeutic composition containing the compound oleuropeine or one of the derivatives thereof | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA) (FR) | 2012-03-20 | — | — | US | disclosed |
| EP-1617836-B1 | NUTRITIONAL OR THERAPEUTIC COMPOSITION CONTAINING THE COMPOUND OLEUROPEINE OR ONE OF THE DERIVATIVES THEREOF | AGRONOMIQUE INST NAT RECH (FR) | 2011-11-30 | — | — | EP | disclosed |