Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 6/20 | 0.58 |
| ▸ | BCHE | P06276 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612260 | 0.97 | KDM4E (0.60) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL6894596 | 0.93 | KMT2A (0.65) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL8706463 | 0.93 | KMT2A (0.65) | KDM4EMEN1MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL9833815 | 0.92 | HDAC8 (0.66) | KDM4EMEN1MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL21082974 | 0.89 | KDM4E (0.65) | KDM4EMEN1MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL21082950 | 0.89 | KDM4E (0.65) | KDM4EMEN1MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL21082951 | 0.89 | KDM4E (0.65) | KDM4EMEN1MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL21082953 | 0.89 | KDM4E (0.65) | KDM4EMEN1MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL21082973 | 0.89 | KDM4E (0.65) | KDM4EMEN1MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL21082976 | 0.88 | ACHE (0.65) | KDM4EMEN1MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | COLE BRIDGET M (US) | 2002-07-11 | — | — | US | claimed |
| US-20020091090-A1 | Somatostatin antagonists and agonists | COLE BRIDGET M (US) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | GHSR, GHRHR, SSTR3 | KDM4E 1412/4885MEN1 882/4885MAPT 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.