Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RB1 | P06400 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615032 | 0.78 | PDE10A (0.32) | PDE9A | |
| SCHEMBL18138933 | 0.74 | NPC1 (0.36) | LMNASMN1; SMN2HTR2AALDH1A1HPGD | |
| SCHEMBL11499685 | 0.70 | — | — | |
| SCHEMBL2230518 | 0.69 | ALDH1A1 (0.35) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL11785225 | 0.68 | ALDH1A1 (0.38) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL1388471 | 0.64 | ALDH1A1 (0.35) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL4466423 | 0.64 | ALDH1A1 (0.35) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL8588800 | 0.64 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1POLBMAPTHPGD | |
| SCHEMBL29547 | 0.64 | AHR (0.37) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL29208908 | 0.64 | ACHE (0.41) | LMNASMN1; SMN2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |