SCHEMBL2230518

SCHEMBL2230518

Clc1[c]c2ccccc2[nH]1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 2/20 0.35
GPR3 P46089 1/20 0.35
KDM4E B2RXH2 3/20 0.33
MAPT P10636 2/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
CYP3A4 P08684 1/20 0.33
PSMB8 P28062 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 2/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11785225 0.75 ALDH1A1 (0.38) ALDH1A1HSD17B10GPR3KDM4EMAPT
SCHEMBL29547 0.71 AHR (0.37) ALDH1A1HSD17B10GPR3KDM4EMAPT
SCHEMBL8588800 0.71 ALDH1A1 (0.40) ALDH1A1HSD17B10GPR3KDM4EMAPT
SCHEMBL1388471 0.71 ALDH1A1 (0.35) ALDH1A1HSD17B10GPR3KDM4EMAPT
SCHEMBL4466423 0.71 ALDH1A1 (0.35) ALDH1A1HSD17B10GPR3KDM4EMAPT
SCHEMBL4600217 0.71 KDM4E (0.47) ALDH1A1KDM4EMAPTHPGDMEN1
SCHEMBL28824470 0.70 AHR (0.35) ALDH1A1HSD17B10GPR3KDM4EMAPT
SCHEMBL7620124 0.69 LMNA (0.33) ALDH1A1MAPTHPGDLMNASMN1; SMN2
SCHEMBL7289576 0.68 PSMB8 (0.41) ALDH1A1KDM4EMAPTGRIN2DGRIN3B
SCHEMBL10813818 0.68 ALDH1A1 (0.32) ALDH1A1HSD17B10GPR3KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111533767-A Tetradentate phosphine ligand and preparation method thereof, hydroformylation catalyst and reaction method, and preparation method of 1, 3-propylene glycol 卢海元 2020-08-14 CN claimed
CN-107312715-A A kind of method that two phase process quickly screens Denitrifying Phosphate Accumulating Organisms 武汉理工大学 2017-11-03 CN claimed
CN-107304402-A High-performance mRNA marker detection method 康隽国际生物科技股份有限公司 2017-10-31 CN claimed
CN-107109465-A Diagnosis and treatment of incipient diabetes 马杜·S·马洛 2017-08-29 CN claimed
CN-101535496-B Genetically engineered biological indicator AMERICAN STERILIZER CO. (US) 2015-12-02 CN claimed
CN-104111331-B Antibody chip for detecting compositae plant virus diseases, and kit and method of antibody chip INSPECTION AND QUARANTINE COMPREHENSIVE TECHNOLOGY CT GANSU ENTRY EXIT INSPECTION AND QUARANTINE BER 2015-05-27 CN claimed
CN-101541944-B Sterilization indicator AMERICAN STERILIZER CO 2013-05-22 CN claimed
US-4870087-A Indole containing, 2-thienyl-1,2,3,6-tetrahydropyridyls and their pharmaceutical use MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-09-26 US claimed
US-4617309-A Sulfur-containing indole derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-10-14 US claimed
CN-116814733-A Rapid detection method for escherichia coli 乌鲁木齐海关技术中心 2023-09-29 CN disclosed
CN-111533767-A Tetradentate phosphine ligand and preparation method thereof, hydroformylation catalyst and reaction method, and preparation method of 1, 3-propylene glycol 卢海元 2020-08-14 CN disclosed
CN-110372798-A Immunogene for HIV vaccine inoculation 埃斯蒂维制药有限公司 2019-10-25 CN disclosed
CN-110291103-A The conjugate of immune response with reduction 韩美药品株式会社 2019-09-27 CN disclosed
CN-104080800-B Immunogens for HIV Vaccination 埃斯蒂维制药有限公司 2019-08-27 CN disclosed
EP-0105397-B1 SULPHURIC INDOLE DERIVATIVES MERCK PATENT GmbH (DE) 1986-07-16 EP disclosed
EP-0165588-A2 Analytical reagent, analytical method, and multilayer chemical-analytical element FUJI PHOTO FILM CO., LTD. (JP) 1985-12-27 EP disclosed
EP-0121716-A1 Indole derivatives MERCK PATENT GmbH (DE) 1984-10-17 EP disclosed
EP-0114603-A1 Indole derivatives MERCK PATENT GmbH (DE) 1984-08-01 EP disclosed
EP-0105397-A1 Sulphuric indole derivatives MERCK PATENT GmbH (DE) 1984-04-18 EP disclosed
EP-0007399-A1 Indolylalkyl amines, pharmaceutical preparations containing them and process for their manufacture MERCK PATENT GmbH (DE) 1980-02-06 EP disclosed