⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15285812 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27986919 | 0.74 | TRPM8 (0.31) | — | |
| SCHEMBL7622272 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL27987295 | 0.72 | TRPM8 (0.34) | — | |
| SCHEMBL7610972 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL27986910 | 0.70 | TSHR (0.38) | — | |
| Bromide SCHEMBL8520238 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL925589 | 0.69 | — | — | |
| SCHEMBL7741897 | 0.69 | — | — | |
| SCHEMBL7616040 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437075-B1 | Polyurethane and polyurea biomaterials for use in medical devices | MEDTRONIC, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6437076-B1 | Polyurethane and polyurea biomaterials for use in medical devices | MEDTRONIC, INC | 2002-08-20 | — | — | US | disclosed |
| EP-0875519-B1 | Polyurethane biomaterials for use in medical devices | MEDTRONIC INC (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6149678-A | Polyurethane and polyurea biomaterials for use in medical devices | MEDTRONIC, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-6111052-A | CONTAINING SACRIFICIAL MOIETIES (E.G., SULFUR-CONTAINING OR PHOSPHORUS-CONTAINING MOIETIES) THAT PREFERENTIALLY OXIDIZE RELATIVE TO OTHER MOIETIES IN THE POLYMER | MEDTRONIC, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-5986034-A | MEDICAL EQUIPMENT WITH CONNECTORS, SHEATHS AND CONDUCTORS | MEDTRONIC, INC. (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0875519-A1 | Biomaterials for use in medical devices | MEDTRONIC, INC. (US) | 1998-11-04 | — | — | EP | disclosed |