Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL1070298 | 0.96 | KDM4E (0.69) | KDM4EALDH1A1HPGDCA9CA1 | |
| Salicylic Acid SCHEMBL31332109 | 0.91 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDCA9CA1 | |
| Salicylic Acid SCHEMBL25288775 | 0.91 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDCA9CA1 | |
| Salicylic Acid SCHEMBL27732770 | 0.89 | ALDH1A1 (0.75) | KDM4EALDH1A1HPGDCA9CA1 | |
| Salicylic Acid SCHEMBL982280 | 0.89 | ALDH1A1 (0.75) | KDM4EALDH1A1HPGDCA9CA1 | |
| Salicylic Acid SCHEMBL30297915 | 0.89 | ALDH1A1 (0.75) | KDM4EALDH1A1HPGDCA9CA1 | |
| Salicylic Acid SCHEMBL30297957 | 0.89 | ALDH1A1 (0.75) | KDM4EALDH1A1HPGDCA9CA1 | |
| Salicylic Acid SCHEMBL28175461 | 0.87 | ALDH1A1 (0.72) | KDM4EALDH1A1HPGDCA9CA1 | |
| Diethylamine SCHEMBL3323938 | 0.86 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDCA9CA1 | |
| Phthalic Acid SCHEMBL4372897 | 0.85 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDCA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926952-B1 | AN ANTIMICROBIAL COMPOSITION, A METHOD FOR THE PREPARATION OF SAME | KEMIRA CHEMICALS OY (FI) | 2002-04-03 | — | — | EP | disclosed |
| EP-0926952-A1 | AN ANTIMICROBIAL COMPOSITION, A METHOD FOR THE PREPARATION OF SAME | KEMIRA CHEMICALS OY (FI) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998003066-A1 | AN ANTIMICROBIAL COMPOSITION, A METHOD FOR THE PREPARATION OF SAME | KEMIRA CHEMICALS OY (FI) | 1998-01-29 | — | — | WO | disclosed |