Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL1070298 | 0.90 | KDM4E (0.69) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| Salicylic Acid SCHEMBL7620792 | 0.86 | KDM4E (0.64) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| Dimethylamine SCHEMBL6883348 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| Methyl Alcohol SCHEMBL8606279 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| Phthalic Acid SCHEMBL5875380 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| Phthalic Acid SCHEMBL4372897 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL1334176 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL6882868 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| Diethylamine SCHEMBL16335615 | 0.84 | LMNA (0.64) | ALDH1A1KDM4EHPGDKMT2ACA1 | |
| SCHEMBL11665831 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993838-A | Method for producing diethylamino hydroxybenzoyl hexyl benzoate | AS科技有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-102448295-A | Method for combating harmful fungi | BASF SE | 2012-05-09 | — | — | CN | claimed |
| EP-1506159-B1 | METHOD FOR PRODUCING 2-(4-N, N-DIALKYLAMINO-2-HYDROXYBENZOYL)BENZOATES | BASF AG (DE) | 2007-09-19 | — | — | EP | claimed |
| US-20050165099-A1 | Method for producing 2-(4-n,n-dialkylamino-2-hydroxybenzol)benzoates | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-28 | — | — | US | claimed |
| EP-0853078-B1 | Purification process of keto acids | CIBA SC HOLDING AG (CH) | 2000-08-16 | — | — | EP | claimed |
| JP-58173160-A | — | — | None | — | — | JP | disclosed |
| JP-6049008-A | — | — | None | — | — | JP | disclosed |
| CN-113993838-A | Method for producing diethylamino hydroxybenzoyl hexyl benzoate | AS科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| WO-2021071033-A1 | METHOD FOR PREPARING DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE | (주)에이에스텍 | 2021-04-15 | — | — | WO | disclosed |
| US-9550727-B2 | Method for the crystallization of 2-(4-N,N-diethyl amino-2-hydroxy-benzoyl)-benzoic acid-n-hexyl ester | BASF SE (DE) | 2017-01-24 | — | — | US | disclosed |
| CN-102448295-B | The method of control harmful fungoid | BASF SE (DE) | 2015-11-25 | — | — | CN | disclosed |
| US-20140349115-A1 | Method for the crystallization of 2-(4-N,N-diethyl Amino-2-hydroxy-benzoyl)-benzoic acid-n-hexyl ester | BASF SE (DE) | 2014-11-27 | — | — | US | disclosed |
| WO-2000051967-A1 | OXYALKYLENE-SUBSTITUTED AMINOPHENOL INTERMEDIATE | MILLIKEN & COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| US-6040482-A | Oxyalkylene-substituted aminophenol intermediate | MILLIKEN & COMPANY (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0511019-B1 | Method of producing keto acids | MITSUI CHEMICALS INC (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0858993-A1 | Method of producing keto acids | Mitsui Chemicals, Inc. (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5371285-A | Method of producing keto acids | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| JP-H0649008-A | PRODUCTION OF KETO-ACID | MITSUI PETROCHEM IND LTD | 1994-02-22 | — | — | JP | disclosed |
| EP-0511019-A2 | Method of producing keto acids | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| JP-S58173160-A | NOVEL FLUORAN DERIVATIVE | RICOH CO LTD | 1983-10-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165099-A1 | Method for producing 2-(4-n,n-dialkylamino-2-hydroxybenzol)benzoates | ADH1C, ADH5, ADH1A | ALDH1A1 7/4885KDM4E 1270/4885HPGD 298/4885 |
| US-20140349115-A1 | Method for the crystallization of 2-(4-N,N-diethyl Amino-2-hydroxy-benzoyl)-benzoic acid-n-hexyl ester | HAO2, HACL2, HAAO | ALDH1A1 2950/4885KDM4E 1272/4885HPGD 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.