Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619693 | 0.85 | ALDH1A1 (0.49) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL10526335 | 0.79 | KDM4C (0.50) | KMT2AMEN1NAPRTL3MBTL1ALDH1A1 | |
| SCHEMBL5051470 | 0.78 | SIRT3 (0.56) | KMT2AMEN1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL4581478 | 0.76 | KMT2A (0.52) | KMT2AMEN1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL22492820 | 0.74 | ROCK2 (0.57) | KMT2AMEN1LTA4HLMNANAPRT | |
| SCHEMBL29374289 | 0.73 | SIRT3 (0.55) | KMT2AMEN1LTA4HLMNANAPRT | |
| SCHEMBL15645364 | 0.73 | SIRT3 (0.42) | KMT2AMEN1NAPRTL3MBTL1ALDH1A1 | |
| SCHEMBL8060987 | 0.71 | ALDH1A1 (0.49) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL725064 | 0.71 | KMT2A (0.80) | KMT2AMEN1LTA4HLMNANAPRT | |
| SCHEMBL2745986 | 0.69 | KMT2A (0.47) | KMT2AMEN1LTA4HLMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353009-B1 | TREATMENT OF GOUT WITH ANTIINFLAMMATORY AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6103870-A | INHIBITS BINDING BETWEEN VLA-4 RECEPTOR EXPRESSED ON INFLAMMATORY LEUKOCYTES AND FIBRONECTIN CS-1 PEPTIDE EXPRESSED ON ENDOTHELIAL CELLS; ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; TREATMENT OF ASTHMA | CYTEL CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |