Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060987 | 0.89 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1GAAAPP | |
| SCHEMBL64069 | 0.78 | AKR1C3 (0.57) | KMT2AMEN1AKR1C3ALDH1A1GAA | |
| SCHEMBL1331831 | 0.78 | AKR1C3 (0.57) | KMT2AMEN1AKR1C3ALDH1A1GAA | |
| SCHEMBL7850570 | 0.77 | AKR1C3 (0.62) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL7824045 | 0.77 | AKR1C3 (0.62) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL5700207 | 0.76 | KMT2A (0.55) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL1643213 | 0.76 | ALDH1A1 (0.65) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL20385461 | 0.76 | KMT2A (0.55) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL8693095 | 0.76 | KMT2A (0.55) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL7621095 | 0.76 | KMT2A (0.46) | KMT2AMEN1KDM4CKDM4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287428-A1 | Novel Heterocyclidene Acetamide Derivative | MOCHIDA PHARMACEUTICAL CO.,LTD (JP) | 2008-11-20 | — | — | US | disclosed |
| US-4617187-A | USING COENZYME Q10; SKING DISORDERS | EISAI CO., LTD. (JP) | 1986-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287428-A1 | Novel Heterocyclidene Acetamide Derivative | TRPV1, TRPV3, TRPA1 | KMT2A 3094/4885MEN1 4073/4885KDM4C 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.