Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626298 | 0.89 | CYP3A4 (0.56) | CYP3A4CYP2D6ADAM17TRPV1HTT | |
| SCHEMBL7626328 | 0.79 | CYP2D6 (0.44) | CYP3A4CYP2D6ADAM17TRPV1MAPT | |
| SCHEMBL7624331 | 0.76 | SLC6A2 (0.51) | CYP3A4CYP2D6ADAM17MAPTALDH1A1 | |
| SCHEMBL7625264 | 0.74 | DRD1 (0.54) | CYP3A4CYP2D6MAPTLMNAMAPK1 | |
| Trepipam SCHEMBL29374758 | 0.73 | CYP2D6 (1.00) | CYP3A4CYP2D6MAPTMAPK1THPO | |
| Trepipam SCHEMBL11704977 | 0.73 | CYP2D6 (1.00) | CYP3A4CYP2D6MAPTMAPK1THPO | |
| SCHEMBL11717530 | 0.72 | CYP2D6 (0.71) | CYP3A4CYP2D6TRPV1HTTMAPT | |
| SCHEMBL7626253 | 0.71 | ALDH1A1 (0.53) | HTTMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL11712657 | 0.71 | CYP3A4 (0.72) | CYP3A4CYP2D6TRPV1HTTDPP4 | |
| SCHEMBL7621097 | 0.71 | CYP3A4 (0.58) | CYP3A4CYP2D6ADAM17TRPV1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | CHACONNE NSI CO., LTD. (KR) | 2002-02-14 | — | — | US | claimed |
| WO-2001095856-A2 | UREA DERIVATIVE USEFUL AS AN ANTI-CANCER AGENT AND PROCESS FOR PREPARING SAME | CHACONNE NSI CO., LTD. (KR) | 2001-12-20 | — | — | WO | claimed |
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | CHACONNE NSI CO., LTD. (KR) | 2002-02-14 | — | — | US | disclosed |
| WO-2001095856-A2 | UREA DERIVATIVE USEFUL AS AN ANTI-CANCER AGENT AND PROCESS FOR PREPARING SAME | CHACONNE NSI CO., LTD. (KR) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | UTS2R, SLC14A1, URB2 | CYP3A4 1639/4885CYP2D6 1945/4885ADAM17 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.