SCHEMBL762134

SCHEMBL762134

c1ccc(N(c2ccc3c(-c4ccc5ccccc5c4)c4cc(N(c5ccccc5)c5cccc6ccccc56)ccc4c(-c4ccc5ccccc5c4)c3c2)c2cccc3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.35
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
DHFR P00374 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
ACMSD Q8TDX5 1/20 0.32
PDE9A O76083 1/20 0.32
ALOX5 P09917 1/20 0.31
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
GSTP1 P09211 1/20 0.31
FABP3 P05413 1/20 0.30
FABP4 P15090 1/20 0.30
FABP5 Q01469 1/20 0.30
PIM1 P11309 1/20 0.30
HPRT1 P00492 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13333637 0.99 SIGMAR1 (0.35) SIGMAR1CYP1A1CYP1B1DHFRGPR84
SCHEMBL14464129 0.97 ESR1 (0.35) SIGMAR1CYP1A1CYP1B1DHFRGPR84
SCHEMBL13333760 0.97 ESR1 (0.35) SIGMAR1CYP1A1CYP1B1DHFRGPR84
SCHEMBL13333917 0.96 ESR1 (0.34) SIGMAR1CYP1A1CYP1B1DHFRGPR84
SCHEMBL13333592 0.95 ESR1 (0.33) SIGMAR1CYP1A1CYP1B1DHFRGPR84
SCHEMBL13333756 0.95 ESR1 (0.36) SIGMAR1CYP1A1CYP1B1GPR84HSD17B1
SCHEMBL12571728 0.95 SIGMAR1 (0.35) SIGMAR1CYP1A1CYP1B1GPR84HSD17B1
SCHEMBL12014708 0.95 SIGMAR1 (0.35) SIGMAR1CYP1B1DHFRHSD17B1HSD17B2
SCHEMBL14099642 0.95 CYP1A1 (0.35) SIGMAR1CYP1A1CYP1B1DHFRGPR84
SCHEMBL15762768 0.94 SIGMAR1 (0.32) SIGMAR1CYP1A1CYP1B1DHFRGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10273404-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2019-04-30 US disclosed
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
WO-2016072691-A1 ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE USING COMPOSITION FOR ORGANIC ELECTRONIC DEVICE 덕산네오룩스 주식회사 2016-05-12 WO disclosed
US-8835019-B2 Organic light emitting device having an electron transport-emission layer and method of preparing the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-09-16 US disclosed
US-8835019-B2 Organic light emitting device having an electron transport-emission layer and method of preparing the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-09-16 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20090251049-A1 Organic electroluminescent device utilizing organic electroluminescent compounds GRACEL DISPLAY INC. (KR) 2009-10-08 US disclosed
WO-2009066814-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND DISPLAY DEVICE CONTAINING THE SAME GRACEL DISPLAY INC. (KR) 2009-05-28 WO disclosed
US-20090128010-A1 Green Electroluminescent Compounds and Organic Electroluminescent Device Using the Same HYUN SEUNG-HAK 2009-05-21 US disclosed
US-20090128010-A1 Green Electroluminescent Compounds and Organic Electroluminescent Device Using the Same HYUN SEUNG-HAK 2009-05-21 US disclosed
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-03-26 US disclosed
US-20080299365-A1 ORGANIC LIGHT EMITTING DEVICE AND METHOD OF PREPARING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2008-12-04 US disclosed
US-20080299365-A1 ORGANIC LIGHT EMITTING DEVICE AND METHOD OF PREPARING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2008-12-04 US disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed
WO-2007021117-A1 GREEN ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090128010-A1 Green Electroluminescent Compounds and Organic Electroluminescent Device Using the Same OCIAD1, OCIAD2, OPA1 SIGMAR1 2144/4885CYP1A1 28/4885CYP1B1 18/4885
US-20090251049-A1 Organic electroluminescent device utilizing organic electroluminescent compounds OCIAD2, OCIAD1, LAGE3 SIGMAR1 2890/4885CYP1A1 1391/4885CYP1B1 1432/4885
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same XPOT, ALAD, APRT SIGMAR1 3640/4885CYP1A1 46/4885CYP1B1 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.