SCHEMBL7621847

SCHEMBL7621847

O=S(=O)(NCCO)c1ccc(S(=O)(=O)NCCO)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.75
CYP2C19 P33261 2/20 0.75
PKM P14618 6/20 0.67
GAA P10253 2/20 0.67
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPT P10636 2/20 0.54
NEK1 Q96PY6 1/20 0.54
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
POLB P06746 1/20 0.53
NAMPT P43490 1/20 0.53
KDM4E B2RXH2 2/20 0.52
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CA12 O43570 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA1 P00915 1/20 0.52
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624023 0.94 ALDH1A1 (0.68) ALDH1A1CYP2C19PKMGAAMEN1
SCHEMBL3377119 0.90 ALDH1A1 (0.66) ALDH1A1CYP2C19PKMGAAMEN1
SCHEMBL5099645 0.90 ALDH1A1 (0.64) ALDH1A1CYP2C19PKMGAAMEN1
SCHEMBL2563975 0.90 CYP3A4 (0.70) ALDH1A1CYP2C19PKMGAACYP3A4
SCHEMBL3279019 0.90 ALDH1A1 (0.70) ALDH1A1CYP2C19PKMGAAMEN1
SCHEMBL14278885 0.90 ALDH1A1 (0.64) ALDH1A1CYP2C19PKMGAAMEN1
SCHEMBL1348420 0.90 ALDH1A1 (0.64) ALDH1A1CYP2C19PKMGAAMEN1
SCHEMBL606283 0.89 ALDH1A1 (0.68) ALDH1A1CYP2C19PKMGAAKDM4E
SCHEMBL9121912 0.88 CYP2C19 (0.69) ALDH1A1CYP2C19PKMGAAMEN1
SCHEMBL19392410 0.88 ALDH1A1 (0.62) ALDH1A1CYP2C19PKMGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929590-B1 HYDROXY-PHENOXYETHER POLYMER THERMOPLASTIC COMPOSITES DOW CHEMICAL CO (US) 2002-05-29 EP disclosed
EP-1028989-A1 HYDROXY ETHER POLYMERS AS THERMOPLASTIC BARRIER RESINS THE DOW CHEMICAL COMPANY (US) 2000-08-23 EP disclosed
US-6011111-A REINFORCING FIBERS; COMPOSITES CAN BE MOLDED INTO SHAPED ARTICLES USEFUL FOR STRUCTURAL MATERIALS AND PARTS BY CONVENTIONAL THERMOFORMING OR OTHER FABRICATION TECHNIQUES. THE DOW CHEMICAL COMPANY (US) 2000-01-04 US disclosed
EP-0929590-A1 HYDROXY-PHENOXYETHER POLYMER THERMOPLASTIC COMPOSITES THE DOW CHEMICAL COMPANY (US) 1999-07-21 EP disclosed
WO-1999023134-A1 HYDROXY ETHER POLYMERS AS THERMOPLASTIC BARRIER RESINS THE DOW CHEMICAL COMPANY (US) 1999-05-14 WO disclosed
WO-1998014498-A1 HYDROXY-PHENOXYETHER POLYMER THERMOPLASTIC COMPOSITES THE DOW CHEMICAL COMPANY (US) 1998-04-09 WO disclosed
US-5686551-A DIHYDROXYSTILBENES, DIGLYCIDYL ETHERS THE DOW CHEMICAL COMPANY (US) 1997-11-11 US disclosed
EP-0589939-B1 HYDROXY-FUNCTIONAL POLY(ETHER SULFONAMIDES) AS THERMOPLASTIC BARRIER RESINS DOW CHEMICAL CO (US) 1996-03-27 EP disclosed
EP-0589939-A1 HYDROXY-FUNCTIONAL POLY(ETHER SULFONAMIDES) AS THERMOPLASTIC BARRIER RESINS. DOW CHEMICAL CO (US) 1994-04-06 EP disclosed
WO-1993000387-A1 HYDROXY-FUNCTIONAL POLY(ETHER SULFONAMIDES) AS THERMOPLASTIC BARRIER RESINS THE DOW CHEMICAL COMPANY (US) 1993-01-07 WO disclosed
US-5149768-A Catalytic polymerization of N,N*-dialkyl or diaryldisulfonamide and a diepoxide; rigid containers, flexible films; oxygen barrier THE DOW CHEMICAL COMPANY (US) 1992-09-22 US disclosed