SCHEMBL606283

SCHEMBL606283

O=S(=O)(NCCO)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
PKM P14618 2/20 0.68
LMNA P02545 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
KDM4E B2RXH2 1/20 0.68
CYP2C19 P33261 2/20 0.65
TBXA2R P21731 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
KEAP1 Q14145 1/20 0.57
GAA P10253 1/20 0.56
MAPK1 P28482 1/20 0.56
NPSR1 Q6W5P4 1/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
MMP1 P03956 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
GBA1 P04062 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19392403 0.93 ALDH1A1 (0.60) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL7621847 0.89 ALDH1A1 (0.75) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL29909105 0.89 MMP2 (0.65) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL812738 0.88 ALDH1A1 (0.75) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL8349568 0.87 ALDH1A1 (0.79) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL4060764 0.86 ALDH1A1 (0.79) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL9121912 0.86 CYP2C19 (0.69) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL7623885 0.86 CYP2C19 (0.73) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL27739300 0.86 ALDH1A1 (0.57) ALDH1A1PKMLMNASMN1; SMN2KDM4E
SCHEMBL8595157 0.85 ALDH1A1 (0.82) ALDH1A1PKMLMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4563720-A2 ELECTROLYTIC COPPER FOIL HAVING DOUBLE-SIDED LOOSE STRUCTURE, PREPARATION METHOD AND APPLICATION THEREOF Jiujiang Defu Tech Co Ltd (CN) 2025-06-04 EP claimed
CN-117661046-A Electrolytic copper foil with double-sided loose structure and preparation method and application thereof 九江德福科技股份有限公司 2024-03-08 CN claimed
CN-114249980-B Glass fiber reinforced polyamide material for plastic high-pressure water gun and preparation method thereof 上海聚威新材料股份有限公司 2023-03-21 CN claimed
CN-114249979-B Polyamide composition with NTC effect and preparation method thereof 金发科技股份有限公司 2022-08-30 CN claimed
CN-114106669-B Curing agent based on N-hydroxyethyl benzene sulfonamide compound and preparation method and application thereof 镇江牛盾新材料科技有限公司 2022-08-26 CN claimed
CN-114249980-A Glass fiber reinforced polyamide material for plastic high-pressure water gun and preparation method thereof 上海聚威新材料股份有限公司 2022-03-29 CN claimed
CN-114249979-A Polyamide composition with NTC effect and preparation method thereof 金发科技股份有限公司 2022-03-29 CN claimed
WO-2022057210-A1 POLYAMIDE COMPOSITION HAVING NTC EFFECT AND PREPARATION METHOD THEREFOR 金发科技股份有限公司 2022-03-24 WO claimed
CN-114106669-A Curing agent based on N-hydroxyethyl benzene sulfonamide compound and preparation method and application thereof 镇江牛盾新材料科技有限公司 2022-03-01 CN claimed
US-7700654-B2 Isolation of N-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of N-butylbenzenesulfonamide and benzenesulfonamide derivatives for treating benign prostatic hyperplasia and/or prostate carcinoma LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2010-04-20 US claimed
EP-1490367-B1 IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS GLAXO GROUP LTD (GB) 2008-07-23 EP claimed
US-7348339-B2 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent GLAXO GROUP LIMITED (GB) 2008-03-25 US claimed
US-20050197328-A1 Imidazopyridine derivatives as kinase inhibitors GLAXO GROUP LIMITED (GB) 2005-09-08 US claimed
EP-1490367-A1 IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-12-29 EP claimed
EP-0929603-B1 PLASTICISED POLYMER COMPOSITIONS UCB SA (BE) 2003-12-03 EP claimed
WO-2003080610-A1 IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2003-10-02 WO claimed
US-6624218-B2 A blend comprising aromatic plasticizer benzenesulphonamides and semi-crystalline polymer; exhibits a processing temperature equal to or greater than 220 degrees C.; melt material for extrusion and injection molding UCB, S.A. (BE) 2003-09-23 US claimed
US-20020165301-A1 Plasticized polymer compositions UCB, S.A. 2002-11-07 US claimed
EP-0929603-A1 PLASTICISED POLYMER COMPOSITIONS UCB, S.A. (BE) 1999-07-21 EP claimed
WO-1998014513-A1 PLASTICISED POLYMER COMPOSITIONS UCB, S.A. (BE) 1998-04-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050197328-A1 Imidazopyridine derivatives as kinase inhibitors NR4A3, XDH, MAPK8 ALDH1A1 4524/4885PKM 805/4885LMNA 2461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.