Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621847 | 0.90 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL4703731 | 0.89 | CA12 (0.71) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL5567042 | 0.88 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL19392364 | 0.87 | LMNA (0.61) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL30490037 | 0.86 | CA12 (0.67) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL8213969 | 0.86 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL2627764 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL7624023 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL7094852 | 0.84 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL7201051 | 0.84 | ALDH1A1 (0.86) | ALDH1A1MEN1KMT2ACA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249979-B | Polyamide composition with NTC effect and preparation method thereof | 金发科技股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114249979-A | Polyamide composition with NTC effect and preparation method thereof | 金发科技股份有限公司 | 2022-03-29 | — | — | CN | claimed |
| WO-2022057210-A1 | POLYAMIDE COMPOSITION HAVING NTC EFFECT AND PREPARATION METHOD THEREFOR | 金发科技股份有限公司 | 2022-03-24 | — | — | WO | claimed |
| EP-1926737-B1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2017-03-15 | — | — | EP | claimed |
| EP-2038288-B1 | NOVEL 4-AMINO-3-(-AZOLYL-PHENOXYMETHYL)-THIENOÝ3,2¨PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-11-24 | — | — | EP | claimed |
| EP-2038288-A1 | NOVEL 4-AMINO-3-(-AZOLYL-PHENOXYMETHYL)-THIENOÝ3,2¨PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-25 | — | — | EP | claimed |
| EP-1926737-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-06-04 | — | — | EP | claimed |
| US-20080009515-A1 | Substituted thieno[3,2-C]pyridine carboxylic acid derivatives | CHEN YI | 2008-01-10 | — | — | US | claimed |
| WO-2008000697-A1 | NOVEL 4-AMINO-3-(-AZOLYL-PHENOXYMETHYL)-THIENO[3,2]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | claimed |
| WO-2007031428-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-22 | — | — | WO | claimed |
| US-20070060607-A1 | 4-amino-thieno[3,2-c] pyridine-7-carboxylic acid derivatives | BARTKOVITZ DAVID J | 2007-03-15 | — | — | US | claimed |
| EP-0929603-B1 | PLASTICISED POLYMER COMPOSITIONS | UCB SA (BE) | 2003-12-03 | — | — | EP | claimed |
| US-6624218-B2 | A blend comprising aromatic plasticizer benzenesulphonamides and semi-crystalline polymer; exhibits a processing temperature equal to or greater than 220 degrees C.; melt material for extrusion and injection molding | UCB, S.A. (BE) | 2003-09-23 | — | — | US | claimed |
| US-20020165301-A1 | Plasticized polymer compositions | UCB, S.A. | 2002-11-07 | — | — | US | claimed |
| EP-0929603-A1 | PLASTICISED POLYMER COMPOSITIONS | UCB, S.A. (BE) | 1999-07-21 | — | — | EP | claimed |
| WO-1998014513-A1 | PLASTICISED POLYMER COMPOSITIONS | UCB, S.A. (BE) | 1998-04-09 | — | — | WO | claimed |
| US-4929530-A | OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-29 | — | — | US | claimed |
| EP-4444798-A1 | ACID RESISTANT POLYOXYMETHYLENE COMPOSITION AND ARTICLES MADE THEREWITH | Celanese International Corporation (US) | 2024-10-16 | — | — | EP | disclosed |
| US-4568700-A | NONCARCINOGEN | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1986-02-04 | — | — | US | disclosed |
| US-4001279-A | CARRY INSOLUBLE REAGENT SUBSTANCES INTO SOLUTION IN NON-HYDROXYLIC MEDIA; CROWN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060607-A1 | 4-amino-thieno[3,2-c] pyridine-7-carboxylic acid derivatives | BRAF, RAF1, MAP3K7 | ALDH1A1 933/4885MEN1 1791/4885KMT2A 1605/4885 |
| US-20080009515-A1 | Substituted thieno[3,2-C]pyridine carboxylic acid derivatives | UQCRB, UQCRC2, AURKB | ALDH1A1 379/4885MEN1 2324/4885KMT2A 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.