SCHEMBL7622005

SCHEMBL7622005

CC(SC#N)Sc1nc2c(Cl)cccc2s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 2/20 0.50
LMNA P02545 3/20 0.43
PDE10A Q9Y233 1/20 0.43
HPGD P15428 3/20 0.40
MAPT P10636 3/20 0.40
ALDH1A1 P00352 3/20 0.40
GAA P10253 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PKM P14618 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
F2RL3 Q96RI0 3/20 0.40
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPC1 O15118 1/20 0.35
PPARA Q07869 3/20 0.34
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067753 0.79 ALDH1A1 (0.53) LMNAHPGDMAPTALDH1A1GAA
SCHEMBL10815738 0.74 LMNA (0.56) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL7622009 0.72 PSMB8 (0.51) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL10816690 0.70 LMNA (0.51) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL8052231 0.68 LMNA (0.43) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL8045244 0.68 F2RL3 (0.42) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL11367879 0.68 PPARA (0.61) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL23452413 0.67 PSMB8 (1.00) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL2609447 0.67 LMNA (0.56) PSMB8LMNAPDE10AHPGDMAPT
SCHEMBL8043175 0.67 LMNA (0.44) PSMB8LMNAPDE10AHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002059221-A2 ANTIFOULING AGENT COMPRISING A N-PHENYL-N'-2,6-DIFLUOROBENZOYL UREA DERIVATIVE SDS BIOTECH K.K. (JP) 2002-08-01 WO disclosed
EP-0712576-B1 Antifouling agent ASAHI DENKA KOGYO KK (JP) 2000-10-11 EP disclosed
EP-0635209-B1 AQUATIC PEST CONTROL DRUG ASAHI DENKA KOGYO KK (JP) 2000-05-17 EP disclosed
EP-0712576-A1 Antifouling agent ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1996-05-22 EP disclosed
US-5505770-A CONTAINING AT LEAST ONE ALKYLPHENYL ESTER OF PHOSPHOROUS OR PHOSPHORIC ACID ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1996-04-09 US disclosed
US-5472483-A Polysulfide compounds with carriers for protective coating of underwater structures ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1995-12-05 US disclosed
EP-0635209-A1 AQUATIC PEST CONTROL DRUG ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1995-01-25 EP disclosed