SCHEMBL7622009

SCHEMBL7622009

N#CSCCSc1nc2c(Cl)cccc2s1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.51
CYP1A2 P05177 4/20 0.44
LMNA P02545 3/20 0.44
CYP2D6 P10635 3/20 0.44
PDE10A Q9Y233 1/20 0.44
ALDH1A1 P00352 5/20 0.41
HPGD P15428 3/20 0.41
MAPK1 P28482 3/20 0.41
MAPT P10636 3/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.38
RAB9A P51151 1/20 0.38
CYP2C19 P33261 3/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 1/20 0.38
STAT6 P42226 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7198792 0.77 CYP1A2 (0.76) CYP1A2LMNACYP2D6ALDH1A1HPGD
SCHEMBL10816690 0.77 LMNA (0.51) PSMB8CYP1A2LMNACYP2D6PDE10A
SCHEMBL9743835 0.75 ALDH1A1 (0.43) PSMB8CYP1A2LMNACYP2D6PDE10A
SCHEMBL7622005 0.72 PSMB8 (0.50) PSMB8LMNAPDE10AALDH1A1HPGD
SCHEMBL10815738 0.71 LMNA (0.56) PSMB8LMNAPDE10AALDH1A1HPGD
SCHEMBL1414529 0.71 CYP1A2 (0.42) PSMB8CYP1A2CYP2D6ALDH1A1HPGD
SCHEMBL9746266 0.71 CASR (0.46) LMNAALDH1A1HPGDMAPK1MAPT
SCHEMBL23452413 0.68 PSMB8 (1.00) PSMB8LMNAPDE10AALDH1A1HPGD
SCHEMBL9037145 0.68 PSMB8 (0.59) PSMB8LMNAPDE10AALDH1A1HPGD
SCHEMBL9386156 0.66 PSMB8 (0.52) PSMB8CYP1A2CYP2D6ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002059221-A2 ANTIFOULING AGENT COMPRISING A N-PHENYL-N'-2,6-DIFLUOROBENZOYL UREA DERIVATIVE SDS BIOTECH K.K. (JP) 2002-08-01 WO disclosed
EP-0712576-B1 Antifouling agent ASAHI DENKA KOGYO KK (JP) 2000-10-11 EP disclosed
EP-0635209-B1 AQUATIC PEST CONTROL DRUG ASAHI DENKA KOGYO KK (JP) 2000-05-17 EP disclosed
EP-0712576-A1 Antifouling agent ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1996-05-22 EP disclosed
US-5505770-A CONTAINING AT LEAST ONE ALKYLPHENYL ESTER OF PHOSPHOROUS OR PHOSPHORIC ACID ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1996-04-09 US disclosed
US-5472483-A Polysulfide compounds with carriers for protective coating of underwater structures ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1995-12-05 US disclosed
EP-0635209-A1 AQUATIC PEST CONTROL DRUG ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1995-01-25 EP disclosed