Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619180 | 0.84 | KMT2A (0.42) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7622306 | 0.76 | PPARG (0.38) | EPHX2PPARAPPARGACACBMEN1 | |
| SCHEMBL7615213 | 0.75 | MME (0.46) | PPARAPPARGPSMB5CNR2ACACB | |
| SCHEMBL26700528 | 0.71 | GAA (0.40) | PPARAPPARGPSMB5CNR2ACACB | |
| SCHEMBL12906649 | 0.70 | SLC6A2 (0.48) | PPARAPPARGPSMB5ACACBMEN1 | |
| SCHEMBL8481611 | 0.69 | FPR2 (0.41) | PPARAPPARGPSMB5CNR2ACACB | |
| SCHEMBL5036948 | 0.69 | ACACB (0.51) | PSMB5CNR2ACACBCTSCHPGD | |
| SCHEMBL5036248 | 0.69 | ACACB (0.51) | PSMB5CNR2ACACBCTSCHPGD | |
| SCHEMBL6584719 | 0.68 | PPARG (0.39) | EPHX2PPARAPPARGPSMB5MEN1 | |
| SCHEMBL8301284 | 0.68 | PPARG (0.48) | EPHX2PPARAPPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783490-B1 | 1-ACYL-4-ALIPHATIC AMINOPIPERIDINE COMPOUNDS | NOVARTIS AG (CH) | 2002-02-06 | — | — | EP | disclosed |