Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615536 | 0.97 | HRH3 (0.34) | HRH3 | |
| SCHEMBL7614190 | 0.95 | HRH3 (0.31) | HRH3KDM4EPOLBTHRBTDP1 | |
| SCHEMBL7616317 | 0.92 | HRH3 (0.33) | HRH3 | |
| SCHEMBL7622391 | 0.83 | HRH3 (0.31) | HRH3 | |
| SCHEMBL11470650 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL7621907 | 0.76 | — | — | |
| SCHEMBL31366376 | 0.74 | TBXAS1 (0.46) | — | |
| SCHEMBL7613936 | 0.73 | CYP3A4 (0.45) | TDP1 | |
| SCHEMBL7621113 | 0.73 | CYP4F2 (0.47) | TDP1 | |
| SCHEMBL7624059 | 0.70 | HRH3 (0.37) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |