Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.35 |
| ▸ | CCND1 | P24385 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419206 | 0.74 | NQO2 (0.34) | CDK4CCND1 | |
| SCHEMBL3483307 | 0.69 | LMNA (0.33) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL9205092 | 0.69 | CDK4 (0.37) | CDK4CCND1KMT2AKDM4E | |
| SCHEMBL29433250 | 0.67 | CDK4 (0.68) | CDK4CCND1KMT2AHTR2AHTR2C | |
| SCHEMBL1629560 | 0.67 | CDK4 (0.68) | CDK4CCND1KMT2AHTR2AHTR2C | |
| SCHEMBL20973050 | 0.67 | F2RL1 (0.36) | HTR2AHTR2C | |
| SCHEMBL7818229 | 0.67 | TDP1 (0.39) | KMT2AKDM4EMEN1MAPT | |
| SCHEMBL11081014 | 0.63 | ADRA2A (0.50) | CDK4CCND1HTR2AHTR2C | |
| Dimethylamine SCHEMBL8570899 | 0.63 | CDK4 (0.61) | CDK4CCND1KMT2AHTR2AHTR2C | |
| SCHEMBL1440849 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1680338-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | disclosed |