Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621606 | 0.84 | MAPK1 (0.45) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL8180447 | 0.82 | KMT2A (0.45) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL7623076 | 0.78 | MAPK1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL7319178 | 0.70 | TERT (0.54) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL30034756 | 0.69 | MEN1 (0.83) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL7624995 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL1656908 | 0.65 | EPHX2 (0.76) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL4764012 | 0.64 | KMT2A (0.65) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL28463612 | 0.64 | CYP2C9 (0.35) | LMNANPC1RAB9A | |
| SCHEMBL3324450 | 0.64 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444612-B1 | CONTROLLING PLANT DISEASES CAUSED BY FUNGUS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| CN-1315943-A | Use of 5-amino-pyrazol-derivatives for combating micro-organisms | BAYER AG (DE) | 2001-10-03 | — | — | CN | disclosed |
| EP-1107956-A2 | USE OF 5-AMINO-PYRAZOL-DERIVATIVES FOR COMBATING MICRO-ORGANISMS | BAYER AG (DE) | 2001-06-20 | — | — | EP | disclosed |
| US-6100288-A | EFFICIENCY; PESTICIDES, AGRICULTURE, STORAGE, HYGIENE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| WO-2000011951-A2 | USE OF 5-AMINO-PYRAZOL-DERIVATIVES FOR COMBATING MICRO-ORGANISMS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-09 | — | — | WO | disclosed |
| US-5981566-A | FOR CONTROLLING ANIMAL PESTS, IN PARTICULAR INSECTS, ARACHNIDS AND NEMATODES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| US-5843978-A | Acylated 5-aminopyrazoles and the use thereof to combat animal parasites | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| CN-1172479-A | Acylated 5-aminopyrrole | BAYER AG (DE) | 1998-02-04 | — | — | CN | disclosed |
| EP-0802907-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AG (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021653-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |