Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623076 | 0.89 | MAPK1 (0.43) | MAPK1NPC1RAB9AEPHX2LTA4H | |
| SCHEMBL7623232 | 0.84 | MEN1 (0.51) | MAPK1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL7618791 | 0.79 | MAPK1 (0.46) | MAPK1NPC1RAB9AEPHX2LTA4H | |
| SCHEMBL8329943 | 0.76 | NOD2 (0.48) | NPC1RAB9AEPHX2LTA4HCSNK1D | |
| SCHEMBL8773916 | 0.73 | NPY5R (0.44) | MAPK1NPC1RAB9AEPHX2LTA4H | |
| SCHEMBL7624995 | 0.72 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2HTTL3MBTL1ALDH1A1 | |
| SCHEMBL4288466 | 0.72 | SMN1; SMN2 (0.47) | MAPK1NPC1RAB9AEPHX2LTA4H | |
| SCHEMBL8987834 | 0.70 | KMT2A (0.51) | NPC1RAB9AEPHX2LTA4HCSNK1D | |
| SCHEMBL27550688 | 0.68 | NOD2 (0.49) | NPC1RAB9AEPHX2LTA4HCSNK1D | |
| Tolfenpyrad SCHEMBL26416 | 0.68 | RAB9A (0.57) | NPC1RAB9ATSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444612-B1 | CONTROLLING PLANT DISEASES CAUSED BY FUNGUS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| CN-1315943-A | Use of 5-amino-pyrazol-derivatives for combating micro-organisms | BAYER AG (DE) | 2001-10-03 | — | — | CN | disclosed |
| US-6100288-A | EFFICIENCY; PESTICIDES, AGRICULTURE, STORAGE, HYGIENE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| US-5981566-A | FOR CONTROLLING ANIMAL PESTS, IN PARTICULAR INSECTS, ARACHNIDS AND NEMATODES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| US-5843978-A | Acylated 5-aminopyrazoles and the use thereof to combat animal parasites | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| EP-0802907-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AG (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021653-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |