Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12581112 | 0.87 | CYP3A4 (0.50) | KDM4ECYP1A2SCN4ATDP1ALOX15 | |
| SCHEMBL10336842 | 0.83 | CYP1A2 (0.60) | KDM4ECYP1A2TDP1PRSS1PRSS2 | |
| SCHEMBL9437433 | 0.83 | PRSS1 (0.47) | CYP1A2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL9437435 | 0.83 | PRSS1 (0.47) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL13007524 | 0.81 | ADRB2 (0.44) | PRSS1PRSS2PRSS3ADRB2ADRB1 | |
| SCHEMBL18837359 | 0.80 | HTR1B (0.52) | KDM4ECYP1A2KMT2AMEN1LMNA | |
| SCHEMBL22207345 | 0.79 | ALDH1A1 (0.58) | CYP1A2TDP1KMT2AMEN1LMNA | |
| SCHEMBL22207443 | 0.79 | ALDH1A1 (0.58) | CYP1A2TDP1KMT2AMEN1LMNA | |
| SCHEMBL22207131 | 0.79 | ALDH1A1 (0.58) | CYP1A2TDP1KMT2AMEN1LMNA | |
| SCHEMBL22207292 | 0.79 | ALDH1A1 (0.58) | CYP1A2TDP1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841411-B2 | Polymers | BASF SE (DE) | 2014-09-23 | — | — | US | disclosed |
| US-8841411-B2 | Polymers | BASF SE (DE) | 2014-09-23 | — | — | US | disclosed |
| EP-2514736-A1 | Intermediates for Polymers | BASF SE (DE) | 2012-10-24 | — | — | EP | disclosed |
| US-8138303-B2 | Polymers | BASF SE (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138303-B2 | Polymers | BASF SE (DE) | 2012-03-20 | — | — | US | disclosed |
| US-7968872-B2 | Polymers | BASF SE (DE) | 2011-06-28 | — | — | US | disclosed |
| US-7968872-B2 | Polymers | BASF SE (DE) | 2011-06-28 | — | — | US | disclosed |
| US-20110152491-A1 | NOVEL POLYMERS | BASF SE (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110152491-A1 | NOVEL POLYMERS | BASF SE (DE) | 2011-06-23 | — | — | US | disclosed |
| EP-1981929-B1 | NOVEL POLYMERS | BASF SE (DE) | 2010-12-22 | — | — | EP | disclosed |
| US-20100249349-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2010-09-30 | — | — | US | disclosed |
| US-20100249349-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2010-09-30 | — | — | US | disclosed |
| WO-2010006852-A1 | NOVEL POLYMERS | BASF SE (DE) | 2010-01-21 | — | — | WO | disclosed |
| US-20090203866-A1 | Novel Polymers | BASF SE (DE) | 2009-08-13 | — | — | US | disclosed |
| US-20090203866-A1 | Novel Polymers | BASF SE (DE) | 2009-08-13 | — | — | US | disclosed |
| WO-2008012250-A1 | NOVEL POLYMERS | CIBA HOLDING INC. (CH) | 2008-01-31 | — | — | WO | disclosed |
| WO-2007090773-A1 | NOVEL POLYMERS | CIBA HOLDING INC. (CH) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152491-A1 | NOVEL POLYMERS | PLEC, PUF60, VIM | KDM4E 3878/4885CYP1A2 3322/4885SCN4A 3774/4885 |
| US-20090203866-A1 | Novel Polymers | PLEC, PUF60, VIM | KDM4E 3878/4885CYP1A2 3322/4885SCN4A 3774/4885 |
| US-20100249349-A1 | Novel Polymers | OCIAD2, OCIAD1, SLCO4C1 | KDM4E 3738/4885CYP1A2 1169/4885SCN4A 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.