Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050069 | 0.90 | MEN1 (0.67) | KMT2AMEN1NAMPTPOLBCTDSP1 | |
| Hippuric Acid SCHEMBL8957458 | 0.81 | HIF1A (0.59) | KMT2AMEN1POLBGAASMN1; SMN2 | |
| SCHEMBL4070473 | 0.81 | CYP1A1 (0.59) | KMT2AMEN1POLBGAAL3MBTL1 | |
| SCHEMBL679222 | 0.81 | DEGS1 (0.79) | KMT2AMEN1POLBCTDSP1DEGS1 | |
| SCHEMBL19337557 | 0.79 | KCNK3 (0.72) | KMT2AMEN1POLBHTTL3MBTL1 | |
| SCHEMBL11688443 | 0.79 | DEGS1 (0.83) | KMT2AMEN1POLBCTDSP1PPARG | |
| SCHEMBL6567288 | 0.79 | HTT (0.55) | KMT2AMEN1NAMPTPOLBCTDSP1 | |
| SCHEMBL12231039 | 0.79 | NPC1 (0.70) | KMT2AMEN1NAMPTGAAHTT | |
| SCHEMBL31262909 | 0.78 | ERCC1 (0.69) | KMT2AMEN1POLBGAAL3MBTL1 | |
| SCHEMBL30845729 | 0.78 | HDAC3 (0.63) | GAAKDM4ETRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | SCHARPE SIMON LODEWIJK (BE) | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | FAP, CTSC, DPP4 | KMT2A 3602/4885MEN1 3963/4885NAMPT 1272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.